Induction of gastric ulcer and intestinal metaplasia in Mongolian gerbils infected withHelicobacter pylori

Fumihiro Hirayama, Shiro Takagi, Hidenobu Kusuhara, +3

Journal of Gastroenterology

Gastric UlcerGastroenterologyPathologyClinical GastroenterologyGastrointestinal Pathology +3

Infection of Human Hepatocyte Chimeric Mouse With Genetically Engineered Hepatitis B Virus *

Masataka Tsuge, Nobuhiko Hiraga, Hideki Takaishi, +10

Hepatology

Development of poorly differentiated adenocarcinoma and carcinoid due to long-term Helicobacter pylori colonization in Mongolian gerbils

Fumihiro Hirayama, Shiro Takagi, Eiji Iwao, +3

Journal of Gastroenterology

GastroenterologyPathologyMicrobiologyMedicineCancer Research +1

Rapid emergence of telaprevir resistant hepatitis C virus strain from wildtype clone in vivo

Nobuhiko Hiraga, Michio Imamura, Hiromi Abe, +16

Hepatology

Emergence of a Novel Lamivudine-Resistant Hepatitis B Virus Variant with a Substitution Outside the YMDD Motif

Hiromi Yatsuji, Chiemi Noguchi, Nobuhiko Hiraga, +14

Antimicrobial Agents and Chemotherapy

Mutant StrainLamivudine-resistant Mutant StrainsMolecular VirologyViral HepatitisYmdd Mutant Strains +12

Infection of human hepatocyte chimeric mouse with genetically engineered hepatitis C virus and its susceptibility to interferon

Nobuhiko Hiraga, Michio Imamura, Masataka Tsuge, +15

FEBS Letters

Elimination of hepatitis C virus by short term NS3-4A and NS5B inhibitor combination therapy in human hepatocyte chimeric mice

Eiji Ohara, Nobuhiko Hiraga, Michio Imamura, +17

Journal of Hepatology

HepatologyHepatitis CHepatitis C VirusViral HepatitisLiver Physiology +8

Establishment of an infectious genotype 1b hepatitis C virus clone in human hepatocyte chimeric mice

T. Kimura, Michio Imamura, Nobuhiko Hiraga, +18

Journal of General Virology

Infectious Genotype 1BViral ReplicationMolecular VirologyHepatologyHepatitis C +12

Prion removal by nanofiltration under different experimental conditions

Mikihiro Yunoki, Hiroyuki Tanaka, Takeru Urayama, +11

Biologicals

EngineeringPrion RemovalEnvironmental EngineeringMembrane ProcessWater Treatment +2

Potent antibacterial activity of Y-754, a novel benzimidazole compound with selective action against Helicobacter pylori

Eiji Iwao, Yoshito Yokoyama, Fumihiro Hirayama, +1

Journal of Infection and Chemotherapy

Antimicrobial Drug DiscoveryMedicinePotent Antibacterial ActivityNovel Benzimidazole CompoundAntibacterial Agent +8