Tumor Necrosis Factor Signaling Requires iRhom2 to Promote Trafficking and Activation of TACE

Colin Adrain, Markus Zettl, Yonka Christova, +2

Science

Tnf ReleaseApoptosisImmunologyPathologyInnate Immunity +17

Processing of β-Secretase by Furin and Other Members of the Proprotein Convertase Family

John W.M. Creemers, Diana Dominguez, Evelyn Plets, +6

Journal of Biological Chemistry

Thiol isomerases negatively regulate the cellular shedding activity of ADAM17

Sofie H Willems, Christopher J. Tape, Peter Stanley, +5

Biochemical Journal

Chemical BiologyReductive StressProtein FunctionDevelopmental BiologyBiochemistry +12

Limited Redundancy of the Proprotein Convertase Furin in Mouse Liver

Anton Roebroek, Neil A. Taylor, Els Louagie, +7

Journal of Biological Chemistry

Differences in pH Optima and Calcium Requirements for Maturation of the Prohormone Convertases PC2 and PC3 Indicates Different Intracellular Locations for These Events

K I J Shennan, Neil A. Taylor, Joanne L. Jermany, +2

Journal of Biological Chemistry

Pro-pc3 MaturationProtein SecretionMolecular PhysiologyCellular EnzymologyBiochemistry +13

Role of furin in granular acidification in the endocrine pancreas: Identification of the V-ATPase subunit Ac45 as a candidate substrate

Els Louagie, Neil A. Taylor, Daisy Flamez, +8

Proceedings of the National Academy of Sciences

Protein SecretionRegulated SecretionCandidate SubstrateV-atpase Subunit Ac45Cellular Physiology +19

Enhanced Tolerance to Autoimmune Uveitis in CD200-Deficient Mice Correlates with a Pronounced Th2 Switch in Response to Antigen Challenge

Neil A. Taylor, Karen McConnachie, Claudia J. Calder, +4

The Journal of Immunology

Mutations within the propeptide, the primary cleavage site or the catalytic site, or deletion of C-terminal sequences, prevents secretion of proPC2 from transfected COS-7 cells

Neil A. Taylor, K I J Shennan, Daniel F. Cutler, +1

Biochemical Journal

Total dose and frequency of administration critically affect success of nasal mucosal tolerance induction

Hui‐Rong Jiang, Neil A. Taylor, Linda Duncan, +2

British Journal of Ophthalmology

Cyclic AMP produces desensitization of prostacyclin and adenosine A2 receptors in hybrid cell lines but does not affect Gs function

Mary Keen, Eamonn Kelly, Anke Krane, +5

Biochimica et Biophysica Acta (BBA) - Molecular Cell Research

Molecular PhysiologySignal TransductionG Protein-coupled ReceptorCell SignalingAdenosine A2 Receptors +10