Kinetic metrics of 18F-FDG in normal human organs identified by systematic dynamic total-body positron emission tomography

Guobing Liu, Hongrong Xu, Pengcheng Hu, +5

European Journal of Nuclear Medicine and Molecular Imaging

Positron Emission TomographyKinetic MetricsTissue ImagingEngineeringMedical Imaging +7

A sensitive assay for simultaneous determination of plasma concentrations of valganciclovir and its active metabolite ganciclovir by LC/MS/MS

Hongrong Xu, Xuening Li, Wei‐Li Chen, +3

Journal of Chromatography B

Plasma ConcentrationsMedicineActive Metabolite GanciclovirBioanalysisMass Spectrometry +10

Matrine determination and pharmacokinetics in human plasma using LC/MS/MS

Xiaolin Zhang, Hongrong Xu, Wei‐Li Chen, +4

Journal of Chromatography B

MedicineMass SpectrometryHuman PlasmaAnalytical ChemistryLiquid Chromatography +4

Safety, tolerability, pharmacokinetics, and pharmacodynamics of novel glucokinase activator HMS5552: results from a first-in-human single ascending dose study

Lei Sheng, Hongrong Xu, Weili Chen, +10

Drug Design Development and Therapy

Pharmacokinetics, Safety and Tolerability of Chiglitazar, A Novel Peroxisome Proliferator-Activated Receptor (PPAR) Pan-Agonist, in Healthy Chinese Volunteers: A Phase I Study

Hongrong Xu, Jinwen Zhang, Wei‐Li Chen, +2

Clinical Drug Investigation

Pharmacological StudyHealthy Chinese VolunteersPharmacologyPharmacological AgentPharmacotherapy +1

Simultaneous determination of desloratadine and its active metabolite 3-hydroxydesloratadine in human plasma by LC/MS/MS and its application to pharmacokinetics and bioequivalence

Hongrong Xu, Xuening Li, Wei‐Li Chen, +1

Journal of Pharmaceutical and Biomedical Analysis

BiochemistryMedicineMass SpectrometryHuman PlasmaToxicology +9

Determination of eprosartan in human plasma and urine by LC/MS/MS

Xuening Li, Hongrong Xu, Wei‐Li Chen, +3

Journal of Chromatography B

BiochemistryMedicineHuman PlasmaAnalytical ChemistryLiquid Chromatography +3

Pharmacokinetics of rosuvastatin in healthy Chinese volunteers living in China: A randomized, open-label, ascending single- and multiple-dose study

Xuening Li, Hongrong Xu, Wei‐Li Chen, +2

Clinical Therapeutics

Healthy Chinese VolunteersMultiple-dose StudyPharmacologyClinical PharmacologyPharmacotherapy +2

An UHPLC–MS/MS method for simultaneous quantification of human amyloid beta peptides Aβ1-38, Aβ1-40 and Aβ1-42 in cerebrospinal fluid using micro-elution solid phase extraction

Pingping Lin, Wei‐Li Chen, Fei Yuan, +6

Journal of Chromatography B

Cerebrospinal FluidBioanalysisProtein MisfoldingBiomedical AnalysisPeptide Science +6

Safety and immunogenicity of a modified COVID-19 mRNA vaccine, SW-BIC-213, as a heterologous booster in healthy adults: an open-labeled, two-centered and multi-arm randomised, phase 1 trial

Yuzhou Gui, Xuening Li, Jingxin Li, +20

EBioMedicine

VaccinologyVaccine SafetyVaccinationVaccine DevelopmentVaccine Surveillance +7