Apigenin inhibits HGF-promoted invasive growth and metastasis involving blocking PI3K/Akt pathway and β4 integrin function in MDA-MB-231 breast cancer cells

Wei-Jiunn Lee, Wen-Kang Chen, Chau-Jong Wang, +2

Toxicology and Applied Pharmacology

MedicineCancer Cell BiologyCell-matrix InteractionHgf-promoted Invasive GrowthBreast Cancer +6

Inhibitory effect of luteolin on hepatocyte growth factor/scatter factor-induced HepG2 cell invasion involving both MAPK/ERKs and PI3K–Akt pathways

Wei-Jiunn Lee, Lan-Feng Wu, Wen-Kang Chen, +2

Chemico-Biological Interactions

Signal TransductionSignaling PathwayCell RegulationLiver PhysiologyPi3k–akt Pathways +10

Quercetin suppresses the metastatic ability of lung cancer through inhibiting Snail-dependent Akt activation and Snail-independent ADAM9 expression pathways

Jer‐Hwa Chang, Shu-Leung Lai, Wan-Shen Chen, +5

Biochimica et Biophysica Acta (BBA) - Molecular Cell Research

Oncogenic AgentMedicineMetastatic AbilityBronchial NeoplasmSnail-dependent Akt Activation +6

Upregulation of miR-328 and inhibition of CREB-DNA-binding activity are critical for resveratrol-mediated suppression of matrix metalloproteinase-2 and subsequent metastatic ability in human osteosarcomas

Shun‐Fa Yang, Wei-Jiunn Lee, Peng Tan, +4

Oncotarget

Creb-dna-binding ActivityMmp-2 ExpressionPathologyOsteosarcoma CellsCancer Biology +15

N-α-Acetyltransferase 10 Protein Suppresses Cancer Cell Metastasis by Binding PIX Proteins and Inhibiting Cdc42/Rac1 Activity

Kuo‐Tai Hua, Ching‐Ting Tan, Gunnar Johansson, +23

Cancer Cell

Tumor BiologyMedicineInhibiting Cdc42/rac1 ActivityCancer Cell BiologyBinding Pix Proteins +7

α-Solanine Inhibits Invasion of Human Prostate Cancer Cell by Suppressing Epithelial-Mesenchymal Transition and MMPs Expression

Kun-Hung Shen, Alex Chien-Hwa Liao, Jui‐Hsiang Hung, +5

Molecules

Chemoprevention StrategyCancer BiologyTumor BiologyEpithelial-mesenchymal Transitionα-Solanine Remains +16

By inhibiting snail signaling and miR-23a-3p, osthole suppresses the EMT-mediated metastatic ability in prostate cancer

Yu‐Ching Wen, Wei-Jiunn Lee, Peng Tan, +4

Oncotarget

Targeting the SPOCK1-snail/slug axis-mediated epithelial-to-mesenchymal transition by apigenin contributes to repression of prostate cancer metastasis

Ming‐Hsien Chien, Yung-Wei Lin, Yu-Ching Wen, +5

Journal of Experimental & Clinical Cancer Research

Nuclear translocation of PKM2/AMPK complex sustains cancer stem cell populations under glucose restriction stress

Yi-Chieh Yang, Ming‐Hsien Chien, Hsin-Yi Liu, +7

Cancer Letters

Glucose Restriction StressLineage PlasticityCell RegulationMedicineCancer Cell Biology +8

Lipocalin 2 prevents oral cancer metastasis through carbonic anhydrase IX inhibition and is associated with favourable prognosis

Chiao‐Wen Lin, Wei-En Yang, Wei-Jiunn Lee, +8

Carcinogenesis

PathologyCancer BiologyTumor BiologyOral CancerCancer Cell Biology +16