Neratinib after trastuzumab-based adjuvant therapy in HER2-positive breast cancer (ExteNET): 5-year analysis of a randomised, double-blind, placebo-controlled, phase 3 trial

Miguel Martín, Frankie A. Holmes, Bent Ejlertsen, +617

The Lancet Oncology

5-Year AnalysisBreast OncologyOncologyHealth SciencesClinical Trials +8

Restraining Lysosomal Activity Preserves Hematopoietic Stem Cell Quiescence and Potency

Raymond Liang, Tasleem Arif, Svetlana Kalmykova, +12

Cell stem cell

Cell DivisionMedicineGeneticsStem Cell MobilizationHematology +9

Mitochondrial metabolism in hematopoietic stem cells requires functional <scp>FOXO</scp> 3

Pauline Rimmelé, Raymond Liang, Carolina L. Bigarella, +7

EMBO Reports

Stem Cell BiologyDevelopmental BiologyMitochondrial BiogenesisMitochondrial FunctionMedicine +6

Aging-like Phenotype and Defective Lineage Specification in SIRT1-Deleted Hematopoietic Stem and Progenitor Cells

Pauline Rimmelé, Carolina L. Bigarella, Raymond Liang, +8

Stem Cell Reports

Young Sirt1-deleted HscsGeneticsAging-like PhenotypeImmunologyAdult Stem Cell +16

Consistent Patterns of Allelic Loss in Natural Killer Cell Lymphoma

Lisa L. P. Siu, Vivian Chan, John K. C. Chan, +3

American Journal Of Pathology

Lymphoid NeoplasiaAutoimmune DiseaseImmunologyPathologyAutoimmunity +5

FOXO3‐mTOR metabolic cooperation in the regulation of erythroid cell maturation and homeostasis

Xin Zhang, Genís Campreciós, Pauline Rimmelé, +10

American Journal of Hematology

Stable heteroplasmy at the single-cell level is facilitated by intercellular exchange of mtDNA

Anitha D. Jayaprakash, Erica K. Benson, Swapna Gone, +6

Nucleic Acids Research

Comparative GenomicsGeneticsMolecular BiologyGenomicsCellular Physiology +22

Prognostic factors for primary gastrointestinal lymphoma

Raymond Liang, D. Todd, T. K. Chan, +5

Hematological Oncology

A Systems Approach Identifies Essential FOXO3 Functions at Key Steps of Terminal Erythropoiesis

Raymond Liang, Genís Campreciós, Yan Kou, +14

PLoS Genetics

Terminal ErythropoiesisTranscriptional RegulationRbcs ProductionDevelopmental BiologyEnucleation Defects +13

FOXO3 Transcription Factor Is Essential for Protecting Hematopoietic Stem and Progenitor Cells from Oxidative DNA Damage

Carolina L. Bigarella, Jianfeng Li, Pauline Rimmelé, +3

Journal of Biological Chemistry