Fungal metabolite ophiobolin A as a promising anti-glioma agent: In vivo evaluation, structure–activity relationship and unique pyrrolylation of primary amines

Ramesh Dasari, Marco Masi, Romana Lisy, +10

Bioorganic & Medicinal Chemistry Letters

Structure–activity RelationshipBiochemistryMedicinePharmacological AgentPromising Anti-glioma Agent +4

C1,C2-ether derivatives of the Amaryllidaceae alkaloid lycorine: Retention of activity of highly lipophilic analogues against cancer cells

Ramesh Dasari, Laetitia Moreno Y Banuls, Marco Masi, +7

Bioorganic & Medicinal Chemistry Letters

BiochemistryC2-ether DerivativesMedicineHerb-drug InteractionAmaryllidaceae Alkaloid Lycorine +5

Synthetic and Biological Studies of Tubulin Targeting C2‐Substituted 7‐Deazahypoxanthines Derived from Marine Alkaloid Rigidins

Robert Scott, Menuka Karki, Mary Rose Reisenauer, +10

ChemMedChem

Stereoselective total synthesis of clonostachydiol

Udugu Ramulu, Ramesh Dasari, Singanaboina Rajaram, +3

Tetrahedron Asymmetry

Stereoselective Total SynthesisOrganic ChemistryStereoselective SynthesisChemistrySynthetic Chemistry +1

5,10b-Ethanophenanthridine amaryllidaceae alkaloids inspire the discovery of novel bicyclic ring systems with activity against drug resistant cancer cells

Sean Henry, Ria Kidner, Mary Rose Reisenauer, +16

European Journal of Medicinal Chemistry

Medicinal ChemistryHeterocyclicBiochemistryNatural Sciences5,10B-ethanophenanthridine Amaryllidaceae Alkaloids +4

Understanding structure activity relationships of Good HEPES lipids for lipid nanoparticle mRNA vaccine applications

Rebecca Goldman, Namratha Turuvekere Vittala Murthy, Trent P. Northen, +16

Biomaterials

Synthetic and Biological Studies of Sesquiterpene Polygodial: Activity of 9‐Epipolygodial against Drug‐Resistant Cancer Cells

Ramesh Dasari, Annelise De Carvalho, Derek C. Medellin, +20

ChemMedChem

Novel Microtubule-Targeting 7-Deazahypoxanthines Derived from Marine Alkaloid Rigidins with Potent in Vitro and in Vivo Anticancer Activities

Derek C. Medellin, Qiong Zhou, Robert McN. Scott, +14

Journal of Medicinal Chemistry

Vivo Anticancer ActivitiesMedicinal ChemistryLinear C2-substituentsPharmaceutical ChemistryRigidin Analogues +13

Anti-cancer evaluation of carboxamides of furano-sesquiterpene carboxylic acids from the soft coral Sinularia kavarattiensis

Singanaboina Rajaram, Udugu Ramulu, Ramesh Dasari, +7

Bioorganic & Medicinal Chemistry Letters

Medicinal ChemistryBiochemistryBioassay-guided IsolationMedicineNatural Sciences +7

Multicomponent Synthesis of the Medicinally Important Pyrrolo[2,3-d]Pyrimidine Scaffold (Minireview)

Ramesh Dasari, Alexander Kornienko

Chemistry of Heterocyclic Compounds

Combinatorial ChemistryMedicinal ChemistryBioorganic ChemistryNatural SciencesMedicine +4