2-Mercaptoethane sulfonate prevents doxorubicin-induced plasma protein oxidation and TNF-α release: Implications for the reactive oxygen species-mediated mechanisms of chemobrain

Christopher D. Aluise, Sumitra Miriyala, Teresa Noel, +9

Free Radical Biology and Medicine

Redox SignalingBiochemistryMedicineNatural SciencesTnf-α Release +5

Doxorubicin-induced elevated oxidative stress and neurochemical alterations in brain and cognitive decline: protection by MESNA and insights into mechanisms of chemotherapy-induced cognitive impairment (“chemobrain”)

Jeriel T. R. Keeney, Xiaojia Ren, Govind Warrier, +7

Oncotarget

Overexpression of Brain-Derived Neurotrophic Factor Enhances Sensory Innervation and Selectively Increases Neuron Number

Ann M. LeMaster, Robin F. Krimm, Brian M. Davis, +4

Journal of Neuroscience

Mn porphyrin-based superoxide dismutase (SOD) mimic, MnIIITE-2-PyP5+, targets mouse heart mitochondria

Ivan Spasojević, Yumin Chen, Teresa Noel, +6

Free Radical Biology and Medicine

BiochemistryMitochondrial FunctionHeart MitochondriaReactive Oxygen SpecieMedicine +3

Doxorubicin-induced central nervous system toxicity and protection by xanthone derivative of Garcinia Mangostana

Jitbanjong Tangpong, Sumitra Miriyala, Teresa Noel, +3

Neuroscience

MedicineHerbal MedicinePhysiologyHerb-drug InteractionXanthone Derivative +7

Phenylbutyrate, a histone deacetylase inhibitor, protects against Adriamycin-induced cardiac injury

Chotiros Daosukho, Yumin Chen, Teresa Noel, +5

Free Radical Biology and Medicine

CardiomyopathyHeart FailureHistone Deacetylase InhibitorMedicineCardiovascular Pharmacology +5

The triangle of death of neurons: Oxidative damage, mitochondrial dysfunction, and loss of choline-containing biomolecules in brains of mice treated with doxorubicin. Advanced insights into mechanisms of chemotherapy induced cognitive impairment (“chemobrain”) involving TNF-α

Xiaojia Ren, Jeriel T. R. Keeney, Sumitra Miriyala, +6

Free Radical Biology and Medicine

Neurodegenerative DiseasesMitochondrial DysfunctionMedicineApoptosisPharmacology +11

Extracellular Vesicles Released by Cardiomyocytes in a Doxorubicin-Induced Cardiac Injury Mouse Model Contain Protein Biomarkers of Early Cardiac Injury

Chontida Yarana, Dustin Carroll, Jing Chen, +10

Clinical Cancer Research

KEAP1 Is a Redox Sensitive Target That Arbitrates the Opposing Radiosensitive Effects of Parthenolide in Normal and Cancer Cells

Yong Xu, Fang Fang, Sumitra Miriyala, +9

Cancer Research

Chemoprevention StrategyLipid PeroxidationCell DeathRedox HomeostasisCancer Biology +18

Pharmacokinetics of the potent redox-modulating manganese porphyrin, MnTE-2-PyP5+, in plasma and major organs of B6C3F1 mice

Ivan Spasojević, Yumin Chen, Teresa Noel, +5

Free Radical Biology and Medicine

Redox SignalingB6c3f1 MiceBiochemistryMedicinePhysiology +7