The PIDDosome activates p53 in response to supernumerary centrosomes

Luca L. Fava, Fabian Schuler, Valentina C. Sladky, +7

Genes & Development

ChromatinDevelopmental BiologySupernumerary CentrosomesCell DivisionMature Centrosome +11

The NOXA–MCL1–BIM axis defines lifespan on extended mitotic arrest

Manuel D. Haschka, Claudia Soratroi, Susanne Kirschnek, +5

Nature Communications

E2F-Family Members Engage the PIDDosome to Limit Hepatocyte Ploidy in Liver Development and Regeneration

Valentina C. Sladky, Katja Knapp, Claudia Soratroi, +21

Developmental Cell

Developmental BiologyHepatologyMedicineLiver PhysiologyLimit Hepatocyte Ploidy +10

Targeting antiapoptotic A1/Bfl-1 by in vivo RNAi reveals multiple roles in leukocyte development in mice

Eleonora Ottina, Francesca Grespi, Denise Tischner, +6

Blood

Necrosis-like death can engage multiple pro-apoptotic Bcl-2 protein family members

Denise Tischner, Claudia Manzl, Claudia Soratroi, +2

APOPTOSIS

Disease MechanismApoptosisPathogenesisPathologyCell Death +6

BH3-only protein Bmf mediates apoptosis upon inhibition of CAP-dependent protein synthesis

Francesca Grespi, Claudia Soratroi, Gerhard Krumschnabel, +6

Cell Death and Differentiation

Protein FunctionSignal TransductionBh3-only Protein BmfBiochemistryCell Regulation +8

MARCH5-dependent degradation of MCL1/NOXA complexes defines susceptibility to antimitotic drug treatment

Manuel D. Haschka, Gerlinde Karbon, Claudia Soratroi, +3

Cell Death and Differentiation

Expression Level-Dependent Contribution of Glucocorticoid Receptor Domains for Functional Interaction with STAT5

Wolfgang Doppler, Michaela Windegger, Claudia Soratroi, +13

Molecular and Cellular Biology

Stat5 ActivityImmunologyFunctional InteractionGlucocorticoidGlucocorticoid Receptor +17

Regulation and Function of the Cytokine-Inducible SH-2 Domain Proteins, CIS and SOCS3, in Mammary Epithelial Cells

Sibylle Tonko-Geymayer, Olivier Goupille, Martin Tonko, +6

Molecular Endocrinology

CytokineSignal TransductionSocs3 ExpressionCell RegulationSignaling Pathway +13

Death of p53-defective cells triggered by forced mitotic entry in the presence of DNA damage is not uniquely dependent on Caspase-2 or the PIDDosome

Claudia Manzl, Luca L. Fava, Gerhard Krumschnabel, +8

Cell Death and Disease