Pablo G. Longo

The Akt/Mcl-1 pathway plays a prominent role in mediating antiapoptotic signals downstream of the B-cell receptor in chronic lymphocytic leukemia B cells

Pablo G. Longo, Luca Laurenti, Stefania Gobessi et al. · Blood · 2007 · 314 citations · Full text

Inhibition of constitutive and BCR-induced Syk activation downregulates Mcl-1 and induces apoptosis in chronic lymphocytic leukemia B cells

Stefania Gobessi, Luca Laurenti, Pablo G. Longo et al. · Leukemia · 2008 · 195 citations

Hematological Malignancy, Induces Apoptosis, Apoptosis +6

ZAP-70 enhances B-cell–receptor signaling despite absent or inefficient tyrosine kinase activation in chronic lymphocytic leukemia and lymphoma B cells

Stefania Gobessi, Luca Laurenti, Pablo G. Longo et al. · Blood · 2006 · 169 citations

The Syk inhibitor fostamatinib disodium (R788) inhibits tumor growth in the Eμ- TCL1 transgenic mouse model of CLL by blocking antigen-dependent B-cell receptor signaling

Mirza Suljagić, Pablo G. Longo, Sara Bennardo et al. · Blood · 2010 · 142 citations · Full text

The Akt signaling pathway determines the different proliferative capacity of chronic lymphocytic leukemia B-cells from patients with progressive and stable disease

Pablo G. Longo, Luca Laurenti, Stefania Gobessi et al. · Leukemia · 2006 · 140 citations

Hematological Malignancy, Stable Disease, Lymphoid Neoplasia +11