R. J. Heetebrij

New strategy for multi-colour fluorescence in situ hybridisation: COBRA: COmbined Binary RAtio labelling

Tanke Hj, J. Wiegant, RPM van Gijlswijk et al. · European Journal of Human Genetics · 1999 · 201 citations · Full text

Binary Ratio, Engineering, Multi-colour Fluorescence +10

New Antitumor Platinum Compounds Linked to Amino Phosphonic Acids Which Lose the Phosphonate and Tertiary Amine Ligand upon Binding to Nucleic Acids

Marieke J. Bloemink, Bernhard K. Keppler, H Zahn et al. · Inorganic Chemistry · 1994 · 43 citations

Preclinical Therapeutics, Pharmaceutical Science, Altmetric Attention Score +25

Reactions of unsymmetrically substituted derivatives of cisplatin with short oligodeoxynucleotides containing a -GpG- sequence: H-bonding interactions in pGpG moieties cross-linked by an asymmetric platinum complex enhancing the formation of one geometrical isomer

Marieke J. Bloemink, R. J. Heetebrij, Kazumi Inagaki et al. · Inorganic Chemistry · 1992 · 38 citations

Engineering, Altmetric Attention Score, Molecular Biology +16

ULS: a versatile method of labeling nucleic acids for FISH based on a monofunctional reaction of cisplatin derivatives with guanine moieties

J. Wiegant, R.P.M. van Gijlswijk, R. J. Heetebrij et al. · Cytogenetic and Genome Research · 1999 · 38 citations

Platinum(<scp>II</scp>)‐Based Coordination Compounds as Nucleic Acid Labeling Reagents: Synthesis, Reactivity, and Applications in Hybridization Assays

R. J. Heetebrij, Eduard G. Talman, Marcel A van Velzen et al. · ChemBioChem · 2003 · 34 citations

Inorganic Chemistry, Nucleic Acid Chemistry, Engineering +13