Norwalk virus binds to histo-blood group antigens present on gastroduodenal epithelial cells of secretor individuals

Séverine Marionneau‐Lambot, Nathalie Ruvoën, Béatrice Le Moullac‐Vaidye, +6

Gastroenterology

Inhibition of the interaction between the SARS-CoV Spike protein and its cellular receptor by anti-histo-blood group antibodies

Patrice Guillon, Monique Clément, Véronique Sebille, +4

Glycobiology

Meriolins (3-(Pyrimidin-4-yl)-7-azaindoles): Synthesis, Kinase Inhibitory Activity, Cellular Effects, and Structure of a CDK2/Cyclin A/Meriolin Complex

Aude Echalier, Karima Bettayeb, Yoan Ferandin, +9

Journal of Medicinal Chemistry

Bioorganic ChemistryHeterocyclicBiochemistryNatural SciencesMedicine +13

Expression of sialyl-Tn epitopes on β1 integrin alters epithelial cell phenotype, proliferation and haptotaxis

Monique Clément, Jézabel Rocher, Gervaise Loirand, +1

Journal of Cell Science

Synthesis of bile acid derivatives and in vitro cytotoxic activity with pro-apoptotic process on multiple myeloma (KMS-11), glioblastoma multiforme (GBM), and colonic carcinoma (HCT-116) human cell lines

Dominique Brossard, Laïla El Kihel, Monique Clément, +4

European Journal of Medicinal Chemistry

BiochemistryBiliary TractMedicineBile Acid DerivativesMultiple Myeloma +5

New lithocholic and chenodeoxycholic piperazinylcarboxamides with antiproliferative and pro-apoptotic effects on human cancer cell lines

Laïla El Kihel, Monique Clément, Marc‐Antoine Bazin, +3

Bioorganic & Medicinal Chemistry

MedicinePharmacological AgentPharmacotherapyAnti-cancer AgentChenodeoxycholic Piperazinylcarboxamides +6

Butyrate Restores Motile Function and Actin Cytoskeletal Network Integrity in Apc Mutated Mouse Colon Epithelial Cells

Virginie Forest, Monique Clément, Fabrice H.F. Pierre, +2

Nutrition and Cancer

Developmental BiologyColon CarcinogenesisTumor MicroenvironmentCell InteractionColorectal Cancer +13

Focus on the Controversial Activation of Human iNKT Cells by 4-Deoxy Analogue of KRN7000

Vivien Lacône, Julie Hunault, Muriel Pipelier, +11

Journal of Medicinal Chemistry

ImmunologyMolecular BiologyCell DeathHuman Inkt CellsMetathesis Reaction +16

Antimalarial Activity of Axidjiferosides, New β-Galactosylceramides from the African Sponge Axinyssa djiferi

Fereshteh Farokhi, Philippe Grellier, Monique Clément, +6

Marine Drugs

BiochemistryAntiparasitic AgentMedicineBioassay-guided IsolationAntimalarial Activity +9

Inhibition of mTORC1 activity by REDD1 induction in myeloma cells resistant to bortezomib cytotoxicity

Olivier Decaux, Monique Clément, Florence Magrangeas, +5

Cancer Science