LPS-preconditioned mesenchymal stromal cells modify macrophage polarization for resolution of chronic inflammation via exosome-shuttled let-7b

Dongdong Ti, Haojie Hao, Chuan Tong, +7

Journal of Translational Medicine

CD133-directed CAR T cells for advanced metastasis malignancies: A phase I trial

Yao Wang, Meixia Chen, Zhiqiang Wu, +11

OncoImmunology

Bispecific CAR-T cells targeting both CD19 and CD22 for therapy of adults with relapsed or refractory B cell acute lymphoblastic leukemia

Hanren Dai, Zhiqiang Wu, Hejin Jia, +11

Journal of Hematology & Oncology

Optimized tandem CD19/CD20 CAR-engineered T cells in refractory/relapsed B cell lymphoma

Chuan Tong, Yang Liu, Xingyu Ji, +11

Blood

Low-dose decitabine priming endows CAR T cells with enhanced and persistent antitumour potential via epigenetic reprogramming

Yao Wang, Chuan Tong, Hanren Dai, +12

Nature Communications

Human umbilical cord-derived mesenchymal stem cells elicit macrophages into an anti-inflammatory phenotype to alleviate insulin resistance in type 2 diabetic rats

Zongyan Xie, Haojie Hao, Chuan Tong, +8

Stem Cells

Adult Stem CellImmunologyAdipose Tissue MacrophagesInsulin SignalingAnti-inflammatory Phenotype +16

Efficacy and biomarker analysis of CD133-directed CAR T cells in advanced hepatocellular carcinoma: a single-arm, open-label, phase II trial

Hanren Dai, Chuan Tong, Daiwei Shi, +7

OncoImmunology

Anti-EGFR chimeric antigen receptor-modified T cells in metastatic pancreatic carcinoma: A phase I clinical trial

Yang Liu, Yelei Guo, Zhiqiang Wu, +7

Cytotherapy

Multiple intravenous infusions of bone marrow mesenchymal stem cells reverse hyperglycemia in experimental type 2 diabetes rats

Haojie Hao, Jiejie Liu, Jing Shen, +11

Biochemical and Biophysical Research Communications

Regenerative MedicineMedicineStem Cell MobilizationDiabetesHematology +12

Hypoxia Pretreatment of Bone Marrow Mesenchymal Stem Cells Facilitates Angiogenesis by Improving the Function of Endothelial Cells in Diabetic Rats with Lower Ischemia

Jiejie Liu, Haojie Hao, Lei Xia, +9

PLoS ONE

Regenerative MedicineAngiogenesisHypoxia PretreatmentEndothelial CellsMedicine +13