Highly Selective and Orally Active Inhibitors of Type IV Collagenase (MMP-9 and MMP-2):  <i>N</i>-Sulfonylamino Acid Derivatives

Yoshinori Tamura, Fumihiko Watanabe, Takuji Nakatani, +9

Journal of Medicinal Chemistry

Pharmaceutical SciencePharmacotherapyChemical BiologyPharmaceutical ChemistryMolecular Pharmacology +16

Potent Inhibitors of Secretory Phospholipase A2:  Synthesis and Inhibitory Activities of Indolizine and Indene Derivatives

Sanji Hagishita, Masaaki Yamada, Kazuhiro Shirahase, +12

Journal of Medicinal Chemistry

Pyrrolidine Inhibitors of Human Cytosolic Phospholipase A₂

Kaoru Seno, Takayuki Okuno, Koichi Nishi, +19

Journal of Medicinal Chemistry

Pharmaceutical SciencePyrrolidine InhibitorsJapan CiteAltmetric Attention ScoreCellular Pharmacology +15

Prevention of Allergic Inflammation by a Novel Prostaglandin Receptor Antagonist, S-5751

Akinori Arimura, Kiyoshi Yasui, Junji Kishino, +5

Journal of Pharmacology and Experimental Therapeutics

Homology Modeling of Gelatinase Catalytic Domains and Docking Simulations of Novel Sulfonamide Inhibitors

Ryuichi Kiyama, Yoshinori Tamura, Fumihiko Watanabe, +3

Journal of Medicinal Chemistry

Synthesis and in vitro activity of various derivatives of a novel thromboxane receptor antagonist, (.+-.)-(5Z)-7-[3-endo[(phenylsulfonyl)amino]bicyclo[2.2.1]hept-2-exo-yl]heptenoic acid

Masayuki Narisada, Mitsuaki Ohtani, Fumihiko Watanabe, +7

Journal of Medicinal Chemistry

Altmetric Attention ScorePharmacotherapyExperimental PharmacologyPharmaceutical ChemistryVarious Derivatives +15

Total Synthesis of (-)-PA-48153C, a Novel Immunosuppressive 2-Pyranone Derivative

Ken Yasui, Yoshinori Tamura, Takuji Nakatani, +2

The Journal of Organic Chemistry

Pharmaceutical ScienceBioorganic ChemistryAltmetric Attention ScorePharmaceutical ChemistryMolecular Pharmacology +16

Synthetic studies on β-lactam antibiotics. Part 10. Synthesis of 7β-[2-carboxy-2-(4-hydroxyphenyl)acetamido]-7.alpha.-methoxy-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-1-oxa-1-dethia-3-cephem-4-carboxylic acid disodium salt (6059-S) and its related 1-oxacephems

Masayuki Narisada, Tadashi Yoshida, Hiroshi Onoue, +6

Journal of Medicinal Chemistry

Medicinal ChemistryAntimicrobial Drug DiscoveryBioorganic Chemistryβ-Lactam AntibioticsBiochemistry +13

Synthesis and Biological Activity of Various Derivatives of a Novel Class of Potent, Selective, and Orally Active Prostaglandin D₂ Receptor Antagonists. 2. 6,6-Dimethylbicyclo[3.1.1]heptane Derivatives

Susumu Mitsumori, Tatsuo Tsuri, Tsunetoshi Honma, +10

Journal of Medicinal Chemistry

PharmacotherapyChemical BiologyVarious DerivativesPharmaceutical ChemistryChemical Derivative +19

Enantioselective synthesis of S-1452, an orally active potent thromboxane A2 receptor antagonist

Mitsuaki Ohtani, T. MATSUURA, Fumihiko Watanabe, +1

The Journal of Organic Chemistry

Pharmaceutical ScienceAltmetric Attention ScorePharmacotherapyChemistryPharmaceutical Chemistry +17