Total Synthesis and Electrophysiological Properties of Natural (−)‐Perhydrohistrionicotoxin, its Unnatural (+)‐Antipode and their 2‐Depentyl Analogs

Kimio Takahashi, Bernhard Witkop, Arnold Brossi, +2

Helvetica Chimica Acta

Lactam 8Bioorganic ChemistryToxinologyBiochemistryElectrophysiological Properties +11

Synthesis of Pyrrolo[1,2-a]indoles and Related Systems

Tetsuji Kametani, Kimio Takahashi

Heterocycles

Diversity Oriented SynthesisBiosynthesisBioorganic ChemistryEngineeringBiochemistry +13

Synthesis and oral antifungal activity of novel azolylpropanolones and related compounds

Masaru Ogata, Hiroshi Matsumoto, Kimio Takahashi, +5

Journal of Medicinal Chemistry

Organic ChemistryKetones XxiAntimicrobial ChemotherapyChemistryHeterocycle Chemistry +16

Synthesis of 2,3-dihydro-1H-pyrrolo[1,2-a]indoles by intramolecular nucleophilic aromatic substitution

Tetsuji Kametani, Kimio Takahashi, Masataka Ihara, +1

Journal of the Chemical Society Perkin Transactions 1

Nickel–aluminium AlloyNatural SciencesDiversity-oriented SynthesisSodium HydrideCorresponding Phenylacetonitriles +6

Synthetic Studies on Mitomycins and Related Compounds

Tetsuji Kametani, Kimio Takahashi

Heterocycles

Combinatorial ChemistryMedicinal ChemistryBiosynthesisBioorganic ChemistryEngineering +12

Probes for a Regulatory Site on the Nicotinic Acetylcholine Receptor‐Channel. Synthesis of (±)‐7‐Debutylperhydrohistrionicotoxin, (±)‐2‐Depentyl‐7‐debutylperhydrohistrionicotoxin, and their Analogues

Wieslaw Gessner, Kimio Takahashi, Bernhard Witkop, +2

Helvetica Chimica Acta

Molecular PharmacologyThiolactam 17Abstract ReactionBiochemistryNatural Sciences +13

Synthesis and antiarrhythmic activity of new 1-[1-[2-[3-{alkylamino}-2-hydroxypropoxy]phenyl]vinyl]-1H-imidazoles and related compounds

Masaru Ogata, Hiroshi Matsumoto, Kimio Takahashi, +5

Journal of Medicinal Chemistry

HeterocyclicIsolated Guinea PigMedicinePhysiologyAsymmetric Synthesis +11

Synthesis of (±)‐<i>trans</i>‐2,5‐Dialkylpyrrolidines from the <i>Lukes‐Šorm</i> Dilactam: Efficient Preparation of (±)‐<i>trans</i>‐2‐Butyl‐5‐heptylpyrrolidine and Analogs Present in Ant Venoms

Wieslaw Gessner, Kimio Takahashi, Arnold Brossi, +2

Helvetica Chimica Acta

Vascular PermeabilityDiversity Oriented SynthesisEngineeringBiochemistryAnalogs Present +11

(.+-.)-2-Depentylperhydrohistrionicotoxin: a new probe for a regulatory site on the nicotinic acetylcholine receptor-channel

Kimio Takahashi, Arthur E. Jacobson, Chin Pong Mak, +7

Journal of Medicinal Chemistry

Studies on the Syntheses of Heterocyclic Compounds. DXLIII¹. An Alternative and Simple Preparation of Tryptamine from L- Tryptophan by Catalytic Decarboxylation with Metal Ion

Tetsuji Kametani, Toshio Suzuki, Kimio Takahashi, +1

Synthesis

EngineeringHeterocyclicHeterocyclic CompoundsOrganic ChemistryMetal Ion +6