Structural basis of a unique interferon-β signaling axis mediated via the receptor IFNAR1

Nicole A. de Weerd, J.P. Vivian, Thao K Nguyen, +10

Nature Immunology

Protein FunctionSignal TransductionSignaling PathwayImmunologyReceptor (Biochemistry) +6

Interferon-ε Protects the Female Reproductive Tract from Viral and Bacterial Infection

Ka Yee Fung, Niamh E. Mangan, Helen Cumming, +14

Science

Inflammasome Adaptor ASC Suppresses Apoptosis of Gastric Cancer Cells by an IL18-Mediated Inflammation-Independent Mechanism

Virginie Deswaerte, Paul M. Nguyen, Alison C. West, +16

Cancer Research

Necroptosis is dispensable for the development of inflammation-associated or sporadic colon cancer in mice

Silvia Álvarez-Díaz, Adele Preaudet, André L. Samson, +8

Cell Death and Differentiation

InflammationTumor BiologyApoptosisImmunologyPathology +8

Cooperation between Monocyte-Derived Cells and Lymphoid Cells in the Acute Response to a Bacterial Lung Pathogen

A Brown, Chao Yang, Ka Yee Fung, +5

PLoS Pathogens

Acute Lung InjuryInflammatory Lung DiseaseMicrobial PathogensLung InflammationAdaptive Immune System +20

Defining the distinct, intrinsic properties of the novel type I interferon, IFNϵ

Sebastian A. Stifter, Antony Y. Matthews, Niamh E. Mangan, +13

Journal of Biological Chemistry

Novel TypePhysicsNatural SciencesApplied PhysicsMolecular Biology +1

Phasevarion-Regulated Virulence in the Emerging Pediatric Pathogen Kingella kingae

Yogitha N. Srikhanta, Ka Yee Fung, Georgina L. Pollock, +3

Infection and Immunity

Structures of the interleukin 11 signalling complex reveal gp130 dynamics and the inhibitory mechanism of a cytokine variant

Riley D. Metcalfe, Eric Hanssen, Ka Yee Fung, +10

Nature Communications

Il-6 Family CytokineCytokine VariantImmunologyImmune RegulationImmunologic Mechanism +16

S100 family proteins are linked to organoid morphology and EMT in pancreatic cancer

Ronnie Ren Jie Low, Ka Yee Fung, Hugh Gao, +14

Cell Death and Differentiation

Mutagenesis and Functional Analysis of the Bacterial Arginine Glycosyltransferase Effector NleB1 from Enteropathogenic Escherichia coli

Tania Wong Fok Lung, Cristina Giogha, Kristina Creuzburg, +6

Infection and Immunity

Protein SecretionImmunologyGlycobiologyMolecular BiologyCell Death +21