A Novel Murine Model of Severe Pulmonary Arterial Hypertension

Loredana Ciuclan, Olivier Bonneau, Martin Hussey, +10

American Journal of Respiratory and Critical Care Medicine

Sex-Dependent Influence of Endogenous Estrogen in Pulmonary Hypertension

Kirsty M. Mair, Audrey F. Wright, Nicholas Duggan, +7

American Journal of Respiratory and Critical Care Medicine

Imatinib Attenuates Hypoxia-induced Pulmonary Arterial Hypertension Pathology via Reduction in 5-Hydroxytryptamine through Inhibition of Tryptophan Hydroxylase 1 Expression

Loredana Ciuclan, Martin Hussey, Victoria J. Burton, +14

American Journal of Respiratory and Critical Care Medicine

Treatment with Anti–Gremlin 1 Antibody Ameliorates Chronic Hypoxia/SU5416–Induced Pulmonary Arterial Hypertension in Mice

Loredana Ciuclan, Kelly-Ann Sheppard, Liqun Dong, +11

American Journal Of Pathology

InflammationHypertensionPulmonary Arterial HypertensionPulmonary CirculationLung Inflammation +7

Reduced response to the formalin test and lowered spinal NMDA glutamate receptor binding in adenosine A2A receptor knockout mice

Martin Hussey, Geoffrey D. Clarke, Catherine Ledent, +2

Pain

Nmda Glutamate ReceptorsPain MedicineSynaptic TransmissionNeurotransmitterMolecular Pain +18

Adenosine A2A receptor signaling regulation of cardiac NADPH oxidase activity

David Ribé, David Sawbridge, Sapna Thakur, +5

Free Radical Biology and Medicine

Cardiac MuscleCardiomyopathySignal TransductionBiochemistryMedicine +7

Optimization of Platelet-Derived Growth Factor Receptor (PDGFR) Inhibitors for Duration of Action, as an Inhaled Therapy for Lung Remodeling in Pulmonary Arterial Hypertension

Duncan Shaw, Ferheen Baig, Ian Bruce, +23

Journal of Medicinal Chemistry

Pdgfr Kinase DomainPulmonary Arterial HypertensionPulmonary CirculationDrug DiscoveryPhysiology +11

Identification of a Novel Allosteric Inhibitory Site on Tryptophan Hydroxylase 1 Enabling Unprecedented Selectivity Over all Related Hydroxylases

Mike Petrassi, Rob Barber, C. Be, +22

Frontiers in Pharmacology

Genetic deletion of the adenosine A2A receptor in mice reduces the changes in spinal cord NMDA receptor binding and glucose uptake caused by a nociceptive stimulus

Martin Hussey, Geoffrey D. Clarke, Catherine Ledent, +2

Neuroscience Letters

Health SciencesMedicinePhysiologyNeuropathic PainNeuropeptide Receptor +11

Ritonavir and Topical Ocular Corticosteroid Induced Cushing’s Syndrome in an Adolescent With HIV-1 Infection

Paul Rainsbury, Jessica L. Sharp, Alison Tappin, +3

The Pediatric Infectious Disease Journal

Ocular DiseaseOphthalmologyNeurovirologyExogenous CorticosteroidsMedicine +7