On the neurotoxicity mechanism of leukoaminochrome o-semiquinone radical derived from dopamine oxidation: mitochondria damage, necrosis, and hydroxyl radical formation

Christian Arriagada, Irmgard Paris, Maria Jose Sanchez de las Matas, +10

Neurobiology of Disease

OxysterolMedicineLipid PeroxidationCell DeathNeuroprotection +8

Aminochrome Induces Disruption of Actin, Alpha-, and Beta-Tubulin Cytoskeleton Networks in Substantia-Nigra-Derived Cell Line

Irmgard Paris, Carolina Perez-Pastene, Sergio Cárdenas, +5

Neurotoxicity Research

Protein FunctionSignal TransductionBiochemistryNatural SciencesMolecular Biology +9

DT-Diaphorase Prevents Aminochrome-Induced Alpha-Synuclein Oligomer Formation and Neurotoxicity

Patricia Muñoz, Sergio Cárdenas, Sandro Huenchuguala, +4

Toxicological Sciences

Majority SncaCell DeathSynaptic SignalingOxidative StressNeuroinflammation +14

Dopamine-Dependent Iron Toxicity in Cells Derived from Rat Hypothalamus

Irmgard Paris, Pedro Martinez-Alvarado, Sergio Cárdenas, +6

Chemical Research in Toxicology

Oxidation of dopamine to aminochrome as a mechanism for neurodegeneration of dopaminergic systems in Parkinson's disease. Possible neuroprotective role of DT-diaphorase.

Rebecca Graumann, Irmgard Paris, Pedro Martinez-Alvarado, +8

PubMed

Dopaminergic SystemsNeurotransmitterFree DopamineRedox BiologyOxidative Stress +15

Plasticity of hippocampus following perinatal asphyxia: Effects on postnatal apoptosis and neurogenesis

Paola Morales, Jenny L. Fiedler, Sergio Andrés, +6

Journal of Neuroscience Research

Monoamine transporter inhibitors and norepinephrine reduce dopamine‐dependent iron toxicity in cells derived from the substantia nigra

Irmgard Paris, Pedro Martinez-Alvarado, Carolina Perez-Pastene, +7

Journal of Neurochemistry

Oogenesis in the bluefin tuna, Thunnus thynnus L.: a histological and histochemical study.

Carmen Sarasquete, Sergio Cárdenas, Canales M L de González, +1

PubMed

OocyteFertilityReproductive BiologyFertilisationEmbryology +19

Adrenalectomy Regulates Apoptotic-Associated Genes in Rat Hippocampus

Monika Greiner, Sergio Cárdenas, C. Parra, +5

Endocrine

Rat HippocampusAdrenal GlandPhysiologyNeuroendocrine MechanismNeuroendocrine Disorder +4

The catecholaminergic RCSN-3 cell line: A model to study dopamine metabolism

Irmgard Paris, Jorge Lozano, Sergio Cárdenas, +12

Neurotoxicity Research

NeurophysiologyMedicinePhysiologyNeurotransmitterNeuropharmacology +10