Sergio Cárdenas

On the neurotoxicity mechanism of leukoaminochrome o-semiquinone radical derived from dopamine oxidation: mitochondria damage, necrosis, and hydroxyl radical formation

Christian Arriagada, Irmgard Paris, Maria Jose Sanchez de las Matas et al. · Neurobiology of Disease · 2004 · 117 citations · Full text

Oxysterol, Medicine, Lipid Peroxidation +10

Aminochrome Induces Disruption of Actin, Alpha-, and Beta-Tubulin Cytoskeleton Networks in Substantia-Nigra-Derived Cell Line

Irmgard Paris, Carolina Perez-Pastene, Sergio Cárdenas et al. · Neurotoxicity Research · 2010 · 82 citations · Full text

Protein Function, Signal Transduction, Biochemistry +11

DT-Diaphorase Prevents Aminochrome-Induced Alpha-Synuclein Oligomer Formation and Neurotoxicity

Patricia Muñoz, Sergio Cárdenas, Sandro Huenchuguala et al. · Toxicological Sciences · 2015 · 75 citations · Full text

Majority Snca, Cell Death, Synaptic Signaling +16

Dopamine-Dependent Iron Toxicity in Cells Derived from Rat Hypothalamus

Irmgard Paris, Pedro Martinez-Alvarado, Sergio Cárdenas et al. · Chemical Research in Toxicology · 2005 · 72 citations · Full text

Oxidation of dopamine to aminochrome as a mechanism for neurodegeneration of dopaminergic systems in Parkinson's disease. Possible neuroprotective role of DT-diaphorase.

Rebecca Graumann, Irmgard Paris, Pedro Martinez-Alvarado et al. · PubMed · 2003 · 72 citations

Dopaminergic Systems, Neurotransmitter, Free Dopamine +17