K. Ekambareswara Rao

Effects of analogs of the DNA minor groove binder Hoechst 33258 on topoisomerase II and I mediated activities

Terry A. Beerman, Mary M. McHugh, Rita Sigmund et al. · Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression · 1992 · 91 citations

Life Sciences, Biochemistry, Molecular Biology +10

Molecular recognition between ligands and nucleic acids: novel pyridine- and benzoxazole-containing agents related to Hoechst 33258 that exhibit altered DNA sequence specificity deduced from footprinting analysis and spectroscopic studies

Yadagiri Bathini, K. Ekambareswara Rao, Regan G. Shea et al. · Chemical Research in Toxicology · 1990 · 76 citations

Pharmacy, Molecular Biology, Pharmacology +17

Netropsin and bis-netropsin analogs as inhibitors of the catalytic activity of mammalian DNA topoisomerase II and topoisomerase cleavable complexes

Terry A. Beerman, Jan M. Woynarowski, Rita Sigmund et al. · Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression · 1991 · 46 citations

Life Sciences, Medicinal Chemistry, Molecular Biology +10

Synthesis of novel thiazole-containing DNA minor groove binding oligopeptides related to the antibiotic distamycin

K. Ekambareswara Rao, Yadagiri Bathini, J. William Lown · The Journal of Organic Chemistry · 1990 · 45 citations

Pharmacy, Medicinal Chemistry, Molecular Biology +9

Molecular recognition between ligands and nucleic acids: DNA binding characteristics of analogs of Hoechst 33258 designed to exhibit altered base and sequence recognition

K. Ekambareswara Rao, J. William Lown · Chemical Research in Toxicology · 1991 · 37 citations

Pharmacy, Medicinal Chemistry, Molecular Biology +17