Pieter H.J. Houba

Concerted changes in transcripts in the prefrontal cortex precede neuropathology in Alzheimer's disease

Koen Bossers, Kerstin T.S. Wirz, Gideon F. Meerhoff et al. · Brain · 2010 · 235 citations · Full text

Life Sciences, Neurobiology, Neuroscience +17

A novel doxorubicin-glucuronide prodrug DOX-GA3 for tumour-selective chemotherapy: distribution and efficacy in experimental human ovarian cancer

Pieter H.J. Houba, Epie Boven, Ida H. van der Meulen‐Muileman et al. · British Journal of Cancer · 2001 · 76 citations · Full text

Medicine, Oncology, Pharmacology +17

Novel anthracycline-spacer-β-glucuronide, -β-glucoside, and -β-galactoside prodrugs for application in selective chemotherapy

Ruben G.G. Leenders, Eric W. P. Damen, Edward J. A. Bijsterveld et al. · Bioorganic & Medicinal Chemistry · 1999 · 58 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +15

Characterization of novel anthracycline prodrugs activated by human β-glucuronidase for use in antibody-directed enzyme prodrug therapy

Pieter H.J. Houba, Ruben G.G. Leenders, Epie Boven et al. · Biochemical Pharmacology · 1996 · 56 citations

Pharmacy, Medicinal Chemistry, Pharmacology +16

Pronounced antitumor efficacy of doxorubicin when given as the prodrug DOX-GA3 in combination with a monoclonal antibody ?-glucuronidase conjugate

Pieter H.J. Houba, Epie Boven, Ida H. van der Meulen‐Muileman et al. · International Journal of Cancer · 2001 · 54 citations · Full text

Pharmacy, Oncology, Pharmacology +17