Concepedia

Author

Pieter H.J. Houba

Vrije Universiteit Amsterdam

Also Known As

P H J Houba, P. H. J. Houba, P.H.J. Houba, Pieter H. J. HOUBA, Pieter H. J. Houba, Pieter H.J Houba, Pieter H.J. Houba, Pieter Houba

11

Publications

609

Citations

10

H-Index

29

Concepts

All Affiliations

Vrije Universiteit AmsterdamRadboud University NijmegenModulation Therapeutics (United States)
PH

About

Pieter H.J. Houba is an author at Vrije Universiteit Amsterdam specializing in medicine, pharmacology, and medicinal chemistry.

Top Concepts

#ConceptH-IndexPublicationsCitations

1

Medicine

6

6

421

2

Natural Sciences

1

1

17

3

Biochemistry

1

1

17

4

Endocrinology

1

1

40

5

Immunology

1

1

56

Pieter H.J. Houba

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10

Publications

599

Citations

10

H-Index

YearCitations

Concerted changes in transcripts in the prefrontal cortex precede neuropathology in Alzheimer's disease

Koen Bossers, Kerstin T.S. Wirz, Gideon F. Meerhoff,

Brain

2010

235

A novel doxorubicin-glucuronide prodrug DOX-GA3 for tumour-selective chemotherapy: distribution and efficacy in experimental human ovarian cancer

Pieter H.J. Houba, Epie Boven, Ida H. van der Meulen‐Muileman,

British Journal of Cancer

2001

74

Novel anthracycline-spacer-β-glucuronide, -β-glucoside, and -β-galactoside prodrugs for application in selective chemotherapy

Ruben G.G. Leenders, Eric W. P. Damen, Edward J. A. Bijsterveld,

Bioorganic & Medicinal Chemistry

1999

58

Characterization of novel anthracycline prodrugs activated by human β-glucuronidase for use in antibody-directed enzyme prodrug therapy

Pieter H.J. Houba, Ruben G.G. Leenders, Epie Boven,

Biochemical Pharmacology

1996

56

Pronounced antitumor efficacy of doxorubicin when given as the prodrug DOX-GA3 in combination with a monoclonal antibody ?-glucuronidase conjugate

Pieter H.J. Houba, Epie Boven, Ida H. van der Meulen‐Muileman,

International Journal of Cancer

2001

54

Novel estrogen-related genes and potential biomarkers of ovarian endometriosis identified by differential expression analysis

Katja Vouk, Tina Šmuc, Christina Guggenberger,

The Journal of Steroid Biochemistry and Molecular Biology

2011

40

Overproduction of prismane protein in <i>Desulfovibrio vulgaris</i> (Hildenborough): evidence for a second <i>S</i>= 1/2‐spin system in the one‐electron reduced state

J.P.W.G. Stokkermans, Pieter H.J. Houba, Antonio J. Pierik,

European Journal of Biochemistry

1992

25

Improved Characteristics of a Human β-Glucuronidase−Antibody Conjugate after Deglycosylation for Use in Antibody-Directed Enzyme Prodrug Therapy

Pieter H.J. Houba, Epie Boven, Hidde J. Haisma

Bioconjugate Chemistry

1996

25

Synthesis and evaluation of novel daunomycin-phosphate-sulfate -β-glucuronide and -β-glucoside prodrugs for application in adept

Ruben G.G. Leenders, Hans W. Scheeren, Pieter H.J. Houba,

Bioorganic & Medicinal Chemistry Letters

1995

17

Distribution and pharmacokinetics of the prodrug daunorubicin-GA3 in nude mice bearing human ovarian cancer xenografts

Pieter H.J. Houba, Epie Boven, Ida H. van der Meulen‐Muileman,

Biochemical Pharmacology

1999

15

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