Mice Deficient for Glucagon Gene-Derived Peptides Display Normoglycemia and Hyperplasia of Islet α-Cells But Not of Intestinal L-Cells

Yoshitaka Hayashi, Michiyo Yamamoto, Hiroyuki Mizoguchi, +5

Molecular Endocrinology

Immune RegulationImmunologyCellular PhysiologyInsulin SignalingGastrointestinal Peptide Hormone +21

DHCR24 Gene Knockout Mice Demonstrate Lethal Dermopathy with Differentiation and Maturation Defects in the Epidermis

Rusella Mirza, Shizu Hayasaka, Yoshiko Takagishi, +9

Journal of Investigative Dermatology

Knockout MouseSkin DevelopmentDevelopmental BiologyMaturation DefectsCutaneous Biology +5

Remodeling of Hepatic Metabolism and Hyperaminoacidemia in Mice Deficient in Proglucagon-Derived Peptides

Chika Watanabe, Yusuke Seino, Hiroki Miyahira, +10

Diabetes

Inhibition of Growth Hormone (GH) Secretion by a Mutant<i>GH-I</i>Gene Product in Neuroendocrine Cells Containing Secretory Granules: An Implication for Isolated GH Deficiency Inherited in an Autosomal Dominant Manner¹

Yoshitaka Hayashi, Michiyo Yamamoto, Sachiko Ohmori, +3

The Journal of Clinical Endocrinology & Metabolism

Wild-type Gh SecretionGeneticsNeuroendocrinologyMolecular GeneticsDisease Gene Identification +15

Ectopic Expression of GIP in Pancreatic β-Cells Maintains Enhanced Insulin Secretion in Mice With Complete Absence of Proglucagon-Derived Peptides

Ayako Fukami, Yusuke Seino, Nobuaki Ozaki, +12

Diabetes

Glucose ToleranceCellular PhysiologyInsulin SignalingGastrointestinal Peptide HormoneMetabolic Syndrome +17

A novel mutation at the donor splice site of intron 3 of the GH-I gene in a patient with isolated growth hormone deficiency

Yoshitaka Hayashi, Takashi Kamijo, Michiyo Yamamoto, +5

Growth Hormone & IGF Research

Developmental BiologyGrowth HormoneMendelian DisorderHuman GrowthGenetic Disorder +8

Growth Hormone Releasing Hormone Receptor (GHRH-R) Gene Mutation in Indian Children with Familial Isolated Growth Hormone Deficiency: A Study from Western India

Meena Desai, Pradnya S. Upadhye, Takashi Kamijo, +5

Journal of Pediatric Endocrinology and Metabolism

Fertility and Pregnancy-Associated ß-Cell Proliferation in Mice Deficient in Proglucagon-Derived Peptides

Chisato Sugiyama, Michiyo Yamamoto, Tomomi Kotani, +3

PLoS ONE

A nonsense mutation (E72X) in growth hormone releasing hormone receptor (GHRHR) gene is the major cause of familial isolated growth hormone deficiency in Western region of India: founder effect suggested by analysis of dinucleotide repeat polymorphism close to GHRHR gene

Takashi Kamijo, Yoshitaka Hayashi, Hisao Seo, +6

Growth Hormone & IGF Research

Growth HormoneHuman GrowthGenetic DisorderGeneticsInherited Metabolic Disease +7

High Protein Diet Feeding Aggravates Hyperaminoacidemia in Mice Deficient in Proglucagon-Derived Peptides

Shinji Ueno, Yusuke Seino, Shihomi Hidaka, +18

Nutrients