A pharmacodynamic and pharmacokinetic assessment of a new alpha‐ adrenoceptor antagonist, doxazosin (UK33274) in normotensive subjects.

HL Elliott, PA Meredith, DJ Sumner, +2

British Journal of Clinical Pharmacology

Digoxin pharmacokinetics: multicompartmental analysis and its clinical implications.

DJ Sumner, AJ Russell

British Journal of Clinical Pharmacology

PharmacotherapyIsotopic Tracer TechniquePhysiologically-based Pharmacokinetic ModelingPharmacokineticsMolecular Pharmacology +19

Verapamil pharmacokinetics and apparent hepatic and renal blood flow.

PA Meredith, HL Elliott, Fabrizio Pasanisi, +3

British Journal of Clinical Pharmacology

ThrombosisHypertensionLiver Blood FlowRenal FunctionPharmacokinetic Modeling +12

Ebastine: the effect of a new antihistamine on psychomotor performance and autonomic responses in healthy subjects.

John Vincent, DJ Sumner, JL Reid

British Journal of Clinical Pharmacology

NeuropsychologyHealthy SubjectsPsychotropic MedicationPsychopharmacologyPharmacotherapy +21

Initial blood pressure as a predictor of the response to antihypertensive therapy.

DJ Sumner, PA Meredith, CA Howie, +1

British Journal of Clinical Pharmacology

A pragmatic approach to the pressor dose‐response as an index of vascular reactivity and adrenoceptor function in man.

DJ Sumner, HL Elliott, John Vincent, +1

British Journal of Clinical Pharmacology

HypertensionPharmacotherapyExperimental PharmacologyPhysiologically-based Pharmacokinetic ModelingPharmacokinetics +16

Comparative pharmacokinetics and pharmacodynamics of cardiac glycosides.

A. W. Kelman, DJ Sumner, M. Lonsdale, +2

British Journal of Clinical Pharmacology

Comparison of the clinical pharmacokinetics and concentration‐effect relationships for medroxalol and labetalol.

HL Elliott, PA Meredith, DJ Sumner, +1

British Journal of Clinical Pharmacology

Systolic time interval v heart rate regression equations using atropine: reproducibility studies.

A. W. Kelman, DJ Sumner, B. Whiting

British Journal of Clinical Pharmacology

Reproducibility StudiesSystolic Time IntervalsCardiovascular PharmacologyCardiovascular FunctionBlood Pressure +17

The prediction of individual systolic time interval v heart rate regression equations.

A. W. Kelman, DJ Sumner, B. Whiting

British Journal of Clinical Pharmacology

Heart RateMaximum Likelihood EstimationCardiovascular DiseaseCardiac MechanicBlood Pressure +13