The reconstituted ‘humanized liver’ in TK-NOG mice is mature and functional

Masami Hasegawa, Kenji Kawai, T Mitsui, +8

Biochemical and Biophysical Research Communications

XenotransplantationHepatologyDevelopmental BiologyLiver PhysiologyReconstituted ‘ +8

Model Analysis of the Concentration-Dependent Permeability of P-gp Substrates

Tatsuhiko Tachibana, Satoshi Kitamura, Motohiro Kato, +4

Pharmaceutical Research

EngineeringDiffusion ResistanceSurface ScienceApplied PhysicsConcentration-dependent Permeability +2

Method for predicting the risk of drug–drug interactions involving inhibition of intestinal CYP3A4 and P-glycoprotein

Tatsuhiko Tachibana, Motohiro Kato, Takao Watanabe, +2

Xenobiotica

Gastrointestinal PharmacologyGastroenterologyPathologyPharmacotherapyDrug–drug Interactions +17

Structure–Permeability Relationship Analysis of the Permeation Barrier Properties of the Stratum Corneum and Viable Epidermis/Dermis of Rat Skin

Koji Yamaguchi, T Mitsui, Yoshinori Aso, +1

Journal of Pharmaceutical Sciences

Structure–permeability Relationship AnalysisSkin DevelopmentCutaneous BiologySkin SubstituteMembrane Biology +8

Selective SGLT2 inhibition by tofogliflozin reduces renal glucose reabsorption under hyperglycemic but not under hypo- or euglycemic conditions in rats

Takumi Nagata, Masanori Fukazawa, Kiyofumi Honda, +10

American Journal of Physiology-Endocrinology and Metabolism

Glucose TitrationRenal InflammationMetabolic SyndromeMolecular PharmacologyRenal Function +17

Prediction of Drug-Drug Interactions based on Time-Dependent Inhibition from High Throughput Screening of Cytochrome P450 3A4 Inhibition

Nobuo Sekiguchi, Atsuko Higashida, Motohiro Kato, +5

Drug Metabolism and Pharmacokinetics

Construction of tangential vectors from normal cardiac magnetic field components

Tsuyoshi Miyashita, Akihiko Kandori, Keiji Tsukada, +4

MagnetismCardiac Magnetic FieldElectrophysiological EvaluationEngineeringTangential Vectors +13

Some issues in discrete approximate solution for stochastic differential equations

Yoshio Komori, T Mitsui

Computers & Mathematics with Applications

Numerical AnalysisEngineeringDiscrete Approximate SolutionStochastic SystemStochastic Calculus +5

Hemodynamic changes in the hepatic circulation after the modulation of the splenic circulation in an in vivo human experimental model

Nobuhisa Akamatsu, Yasuhiko Sugawara, Shouichi Satou, +5

Liver Transplantation

Organ PhysiologySplenic CirculationGastroenterologyVisceral SurgerySurgery +20

<i>In vitro</i>model for the prediction of clinical CYP3A4 induction using HepaRG cells

Akihisa Kaneko, Motohiro Kato, Nobuo Sekiguchi, +3

Xenobiotica