Analysis of mutation in human cells by using an Epstein-Barr virus shuttle system.

Robert B. DuBridge, Po-Cheng Tang, H C Hsia, +3

Molecular and Cellular Biology

Viral ReplicationEngineeringEpstein-barr VirusHuman CellsMedicine +13

High mutation frequency in DNA transfected into mammalian cells.

M P Calos, Jane Lebkowski, Michael R. Botchan

Proceedings of the National Academy of Sciences

High Mutation FrequencyDna DamageReverse GeneticsGeneticsEscherichia Coli +15

Isolation of human sequences that replicate autonomously in human cells.

Patrick J. Krysan, Steven B. Haase, M P Calos

Molecular and Cellular Biology

Viral ReplicationHuman CellViral PersistenceHuman Genomic SequencesHuman Sequences +11

Autonomous DNA replication in human cells is affected by the size and the source of the DNA.

Scott S. Heinzel, Patrick J. Krysan, Chi Thi Du Tran, +1

Molecular and Cellular Biology

ChromatinGenome InstabilityAutonomous ReplicationDnaHuman Cell +13

Transfected DNA is mutated in monkey, mouse, and human cells.

Jane Lebkowski, Robert B. DuBridge, Elizabeth A. Antell, +2

Molecular and Cellular Biology

Viral ReplicationTransgenic Mouse ModelsGeneticsMolecular GeneticsMutation Frequency +17

Replication initiates at multiple locations on an autonomously replicating plasmid in human cells.

Patrick J. Krysan, M P Calos

Molecular and Cellular Biology

Viral ReplicationGeneticsReplication Fork BarrierDna AnalysisMolecular Biology +18

The lacI shuttle: rapid analysis of the mutagenic specificity of ultraviolet light in human cells.

Jane Lebkowski, S. Clancy, J H Miller, +1

Proceedings of the National Academy of Sciences

Ultraviolet LightDna DamageLaci ShuttleGeneticsMolecular Biology +21

Specificity of mutations induced in transfected DNA by mammalian cells.

J H Miller, Jane Lebkowski, Kay S. Greisen, +1

The EMBO Journal

Genome InstabilityDna DamageMedicineGeneticsDna Replication +4

Use of simian virus 40 replication to amplify Epstein-Barr virus shuttle vectors in human cells

Scott S. Heinzel, Patrick J. Krysan, M P Calos, +1

Journal of Virology

Sv40 ReplicationViral ReplicationSv40 T AntigenViral EvolutionMolecular Virology +12

Transcription inhibits the replication of autonomously replicating plasmids in human cells.

Steven B. Haase, Scott S. Heinzel, M P Calos

Molecular and Cellular Biology

Transcriptional RegulationCell RegulationHuman CellsNatural SciencesGenomic Mechanism +13