Aurélien Peru

Discovery of (<i>R</i>)-8-(1-(3,5-Difluorophenylamino)ethyl)-<i>N</i>,<i>N</i>-dimethyl-2-morpholino-4-oxo-4<i>H</i>-chromene-6-carboxamide (AZD8186): A Potent and Selective Inhibitor of PI3Kβ and PI3Kδ for the Treatment of PTEN-Deficient Cancers

Bernard Barlaam, Sabina Cosulich, Sébastien L. Degorce et al. · Journal of Medicinal Chemistry · 2014 · 85 citations · Full text

Pten Deficient Tumors, Pharmacotherapy, Pharmaceutical Chemistry +20

Investigation of (<i>E</i>)-3-[4-(2-Oxo-3-aryl-chromen-4-yl)oxyphenyl]acrylic Acids as Oral Selective Estrogen Receptor Down-Regulators

Sébastien L. Degorce, Andrew Bailey, Rowena Callis et al. · Journal of Medicinal Chemistry · 2015 · 42 citations · Full text

Breast Oncology, Female Reproductive Function, Pharmacotherapy +19

Chemo-Enzymatic Synthesis of Chiral Epoxides Ethyl and Methyl (S)-3-(Oxiran-2-yl)propanoates from Renewable Levoglucosenone: An Access to Enantiopure (S)-Dairy Lactone

Aurélien Peru, Amandine L. Flourat, Christian Gunawan et al. · Molecules · 2016 · 24 citations · Full text

Engineering, Organic Chemistry, Chiral Epoxides Ethyl +16

High‐Yielding Diastereoselective <i>syn</i>‐Dihydroxylation of Protected HBO: An Access to D‐(+)‐Ribono‐1,4‐lactone and 5‐<i>O</i>‐Protected Analogues

Maxime Moreaux, Guillaume Bonneau, Aurélien Peru et al. · European Journal of Organic Chemistry · 2018 · 13 citations · Full text

Versatile Chiral Sugar, Biosynthesis, Derivatives +15

Two-Directional Approach for the Rapid Synthesis of 2,4-Bis-Aminoaryl Pyridine Derivatives

Rémy Morgentin, Bernard Barlaam, Kevin M. Foote et al. · Synthetic Communications · 2011 · 10 citations

Combinatorial Chemistry, Different Approaches, Cross-coupling Reaction +10