Alain Gast

Design and Synthesis of Potent and Highly Selective Thrombin Inhibitors

Kurt Hilpert, Jean Ackermann, David W. Banner et al. · Journal of Medicinal Chemistry · 1994 · 189 citations · Full text

Structural Basis for Allosteric Ligand Recognition in the Human CC Chemokine Receptor 7

K. Jaeger, S. Bruenle, Tobias Weinert et al. · Cell · 2019 · 141 citations · Full text

Epidermal growth factor receptor targeting enhances adenoviral vector based suicide gene therapy of osteosarcoma

M.A. Witlox, Victor W. van Beusechem, Jacques Grill et al. · The Journal of Gene Medicine · 2002 · 52 citations

Thrombin plays a key role in late platelet thrombus growth and/or stability. Effect of a specific thrombin inhibitor on thrombogenesis induced by aortic subendothelium exposed to flowing rabbit blood.

Alain Gast, T. Tschopp, HR Baumgartner · Arteriosclerosis and Thrombosis A Journal of Vascular Biology · 1994 · 46 citations · Full text

Key Role, Rabbit Blood, Immunology +20

Inhibition of clot-bound and free (fluid-phase thrombin) by a novel synthetic thrombin inhibitor (Ro 46-6240), recombinant hirudin and heparin in human plasma

Alain Gast, T. Tschopp, Georg H. Schmid et al. · Blood Coagulation & Fibrinolysis · 1994 · 43 citations