Mechanisms of nitric oxide-mediated neurotoxicity in primary brain cultures

VL Dawson, T. Renee Dawson, DA Bartley, +2

Journal of Neuroscience

Primary Brain CulturesNitric OxideSocial SciencesOxidative StressReactive Nitrogen Specie +14

Opioid peptide enkephalin: immunohistochemical mapping in rat central nervous system.

Rabi Simantov, M. J. Kuhar, G R Uhl, +1

Proceedings of the National Academy of Sciences

Opioid Peptide EnkephalinSynaptic TransmissionSpecific AntiseraMolecular PainMolecular Pharmacology +17

Immunosuppressant FK506 enhances phosphorylation of nitric oxide synthase and protects against glutamate neurotoxicity.

Ted M. Dawson, Joseph Steiner, Valina L. Dawson, +3

Proceedings of the National Academy of Sciences

Nitric OxideImmunologyCell DeathImmunosuppressant Fk506Oxidative Stress +15

The dopamine transporter is localized to dendritic and axonal plasma membranes of nigrostriatal dopaminergic neurons

RA Vaughan, G R Uhl, MJ Kuhar, +1

Journal of Neuroscience

Synaptic TransmissionNeurotransmitterNeurotransmissionSocial SciencesNeurology +15

Dopamine transporter site-directed mutations differentially alter substrate transport and cocaine binding.

S. Kitayama, Shoichi Shimada, H. Eric Xu, +3

Proceedings of the National Academy of Sciences

NeurotransmitterSubstrate TransportMolecular PharmacologyDopamine UptakeNeurochemistry +16

Human immunodeficiency virus type 1 coat protein neurotoxicity mediated by nitric oxide in primary cortical cultures.

Valina L. Dawson, Ted M. Dawson, G R Uhl, +1

Proceedings of the National Academy of Sciences

Primary Cortical CulturesNitric OxideImmunologyRedox BiologyOxidative Stress +18

Parkinsonism-inducing neurotoxin, N-methyl-4-phenyl-1,2,3,6 -tetrahydropyridine: characterization and localization of receptor binding sites in rat and human brain.

Jonathan A. Javitch, G R Uhl, S H Snyder

Proceedings of the National Academy of Sciences

Parkinsonism-inducing NeurotoxinNeurotransmitterSocial SciencesN-methyl-4-phenyl-1,2,3,6 -TetrahydropyridineHigh Receptor Densities +15

Differential expression of preproenkephalin and preprodynorphin mRNAs in striatal neurons: high levels of preproenkephalin expression depend on cerebral cortical afferents

G R Uhl, Bradford Navia, Janice G. Douglas

Journal of Neuroscience

Human kappa opiate receptor second extracellular loop elevates dynorphin's affinity for human mu/kappa chimeras

J B Wang, P. S. Johnson, Jennifer M. Wu, +2

Journal of Biological Chemistry

Somatostatin mRNA: regional variation in hybridization densities in individual neurons

G R Uhl, CA Sasek

Journal of Neuroscience

NeurotransmissionSocial SciencesHybridization DensitiesNeuroendocrine MechanismNeurogenetics +14