CpG DNA is a potent enhancer of systemic and mucosal immune responses against hepatitis B surface antigen with intranasal administration to mice.

Michael J. McCluskie, H. L. Davis

PubMed

ImmunologyImmunodominanceAntigen ProcessingImmune SystemImmunotherapy +18

DNA vaccine for hepatitis B: evidence for immunogenicity in chimpanzees and comparison with other vaccines.

H. L. Davis, Michael J. McCluskie, J. L. Gerin, +1

Proceedings of the National Academy of Sciences

Immune-mediated destruction of transfected muscle fibers after direct gene transfer with antigen-expressing plasmid DNA

H. L. Davis, CL Brazolot Millan

Gene Therapy

XenotransplantationSkeletal MuscleImmunologyDna ReplicationGenetic Engineering +8

Enhancing vaccines with immune stimulatory CpG DNA.

A M Krieg, H. L. Davis

PubMed

VaccinologyVaccinationCpg DnaVaccine DevelopmentMedicine +13

CPG 7909 Adjuvant plus Hepatitis B Virus Vaccination in HIV‐Infected Adults Achieves Long‐Term Seroprotection for Up to 5 Years

Curtis Cooper, Jonathan B. Angel, Isabelle Seguin, +2

Clinical Infectious Diseases

Identification of methylated CpG motifs as inhibitors of the immune stimulatory CpG motifs

Y Chen, Petar Lenert, Risini D. Weeratna, +4

Gene Therapy

ImmunogeneticsSignal TransductionG Protein-coupled ReceptorMethylated Cpg MotifsImmunology +5

Designing gene therapy vectors: avoiding immune responses by using tissue-specific promoters

RD Weeratna, Tong Wu, SM Efler, +2

Gene Therapy

Gene TherapiesIn Vivo Gene TherapyImmunologyGene Therapy VectorsCell Transplantation +9

Mini-dystrophin gene transfer in mdx4cv diaphragm muscle fibers increases sarcolemmal stability

A. Decrouy, J-M Renaud, H. L. Davis, +3

Gene Therapy

Muscle FunctionSkeletal MusclePhysiologyMini-dystrophin Gene TransferMechanotransduction +4

Adjuvant effects of CpG oligodeoxynucleotides on responses against T‐independent type 2 antigens

Jiří Kovařík, Paola Bozzotti, Chantal Tougne, +4

Immunology

Immune-mediated destruction of transfected myocytes following DNA vaccination occurs via multiple mechanisms

Payette Pj, RD Weeratna, M. J. McCluskie, +1

Gene Therapy

VaccinationVaccine DevelopmentDna VaccinationMedicineImmunology +10