Stable antibody expression at therapeutic levels using the 2A peptide

Jianmin Fang, Jingjing Qian, Saili Yi, +4

Nature Biotechnology

Peptide LibraryImmunologyPeptide TherapeuticAntibody ScreeningAntigen Processing +7

Combination of 4-1BB Agonist and PD-1 Antagonist Promotes Antitumor Effector/Memory CD8 T Cells in a Poorly Immunogenic Tumor Model

Shihao Chen, Li‐Fen Lee, Timothy S. Fisher, +12

Cancer Immunology Research

Inhibition of Lymphogenous Metastasis Using Adeno-Associated Virus-Mediated Gene Transfer of a Soluble VEGFR-3 Decoy Receptor

Jianmin Lin, Alshad S. Lalani, Thomas C. Harding, +9

Cancer Research

AngiogenesisOncologyMedicineMelanomaImmunology +11

Vascular Endothelial Growth Factor Blockade Reduces Intratumoral Regulatory T Cells and Enhances the Efficacy of a GM-CSF–Secreting Cancer Immunotherapy

Betty Li, Alshad S. Lalani, Thomas C. Harding, +7

Clinical Cancer Research

Anti–IL-7 receptor-α reverses established type 1 diabetes in nonobese diabetic mice by modulating effector T-cell function

Li‐Fen Lee, Kathryn Logronio, Guang Huan Tu, +12

Proceedings of the National Academy of Sciences

Adaptive Immune SystemAnti–il-7 Receptor-α ReversesT-regulatory CellImmunologyImmune Regulation +25

IL-7 Promotes T _H 1 Development and Serum IL-7 Predicts Clinical Response to Interferon-β in Multiple Sclerosis

Li‐Fen Lee, Robert C. Axtell, Guang Huan Tu, +13

Science Translational Medicine

An Antibody Delivery System for Regulated Expression of Therapeutic Levels of Monoclonal Antibodies In Vivo

Jianmin Fang, Saili Yi, Andrew D. Simmons, +5

Molecular Therapy

Regulated ExpressionImmunocytochemical TechniqueImmunologyBiomedical EngineeringImmunotherapy +16

Antibody responses to galectin-8, TARP and TRAP1 in prostate cancer patients treated with a GM-CSF-secreting cellular immunotherapy

Minh Chau Nguyen, Guang Huan Tu, Kathryn Koprivnikar, +3

Cancer Immunology Immunotherapy

Cancer ImmunosurveillanceProstate Cancer PatientsImmunologyTumor ImmunityImmune Checkpoint Inhibitor +10

Ligand-Blocking and Membrane-Proximal Domain Targeting Anti-OX40 Antibodies Mediate Potent T Cell-Stimulatory and Anti-Tumor Activity

Pamela Zhang, Guang Huan Tu, Jie Wei, +10

Cell Reports

T-regulatory CellImmunologyAntigen ProcessingImmunotherapyTumor Biology +14