W Knepel

Alpha-cell-specific expression of the glucagon gene is conferred to the glucagon promoter element by the interactions of DNA-binding proteins.

Jan Philippé, Daniel J. Drucker, W Knepel et al. · Molecular and Cellular Biology · 1988 · 145 citations · Full text

Genetics, Molecular Genetics, Cellular Physiology +19

Membrane depolarization and calcium influx induce glucagon gene transcription in pancreatic islet cells through the cyclic AMP-responsive element.

Markus Schwaninger, G Lux, R Blume et al. · Journal of Biological Chemistry · 1993 · 116 citations · Full text

Cellular Physiology, Calcium-dependent Action Potentials, Insulin Signaling +20

Transcriptional activation of the rat glucagon gene by the cyclic AMP-responsive element in pancreatic islet cells.

W Knepel, J Chafitz, Joel F. Habener · Molecular and Cellular Biology · 1990 · 91 citations · Full text

Transcriptional Activation, Molecular Physiology, Developmental Biology +15

Effects of a Kappa-Opioid Agonist on Adrenocorticotropic and Diuretic Function in Man

Andreas Pfeiffer, W Knepel, Sandra Braun et al. · Hormone and Metabolic Research · 1986 · 89 citations

Hypertension, Pharmacotherapy, Mr 2034 +21

A pancreatic islet cell-specific enhancer-like element in the glucagon gene contains two domains binding distinct cellular proteins.

W Knepel, Lisa I. Jepeal, Joel F. Habener · Journal of Biological Chemistry · 1990 · 84 citations · Full text

Insulin Signaling, Transcriptional Regulation, Cell Signaling +16