C H June

CD28 costimulation can promote T cell survival by enhancing the expression of Bcl-xL

Lawrence Boise, Andy J. Minn, Patricia J. Noel et al. · Immunity · 1995 · 1.2K citations · Full text

T Cell Survival, Cell Therapy, Adaptive Immune System +8

Inhibition of tyrosine phosphorylation prevents T-cell receptor-mediated signal transduction.

C H June, Mary C. Fletcher, J A Ledbetter et al. · Proceedings of the National Academy of Sciences · 1990 · 501 citations · Full text

Immunology, Immunologic Mechanism, Antigen Processing +17

Increases in tyrosine phosphorylation are detectable before phospholipase C activation after T cell receptor stimulation.

C H June, Mary C. Fletcher, J A Ledbetter et al. · The Journal of Immunology · 1990 · 427 citations

Heterogeneity among T cells in intracellular free calcium responses after mitogen stimulation with PHA or anti-CD3. Simultaneous use of indo-1 and immunofluorescence with flow cytometry.

Peter S. Rabinovitch, C H June, Angelika Grossmann et al. · The Journal of Immunology · 1986 · 366 citations · Full text

Immunocytochemical Technique, Cd4+ Cells, Laboratory Immunology +20

Decreased dependence of myelin basic protein-reactive T cells on CD28-mediated costimulation in multiple sclerosis patients. A marker of activated/memory T cells.

Amy E. Lovett‐Racke, John L. Trotter, Jörg Lauber et al. · Journal of Clinical Investigation · 1998 · 264 citations · Full text

T-regulatory Cell, Immunology, Cd4 T Cell Responses +17