James Michaels

The use of peptones as medium additives for the production of a recombinant therapeutic protein in high density perfusion cultures of mammalian cells

Rüdiger Heidemann, Chun Zhang, Hanshi Qi et al. · Cytotechnology · 2000 · 124 citations

Protection mechanisms of freely suspended animal cells (CRL 8018) from fluid‐mechanical injury. Viscometric and bioreactor studies using serum, pluronic F68 and polyethylene glycol

James Michaels, Jonathan F. Petersen, Larry V. Mclntire et al. · Biotechnology and Bioengineering · 1991 · 100 citations

Analysis of cell‐to‐bubble attachment in sparged bioreactors in the presence of cell‐protecting additives

James Michaels, Jason Nowak, Ameet K. Mallik et al. · Biotechnology and Bioengineering · 1995 · 78 citations

Interfacial properties of cell culture media with cell‐protecting additives

James Michaels, Jason Nowak, Ameet K. Mallik et al. · Biotechnology and Bioengineering · 1995 · 62 citations

Sparging and agitation-induced injury of cultured animals cells: Do cell-to-bubble interactions in the bulk liquid injure cells?

James Michaels, Ameet K. Mallik, Eleftherios T. Papoutsakis · Biotechnology and Bioengineering · 2000 · 59 citations