Arul Shanmugam

Sigma 1 receptor regulates the oxidative stress response in primary retinal Müller glial cells via NRF2 signaling and system xc−, the Na+-independent glutamate–cystine exchanger

Jing Wang, Arul Shanmugam, Shanu Markand et al. · Free Radical Biology and Medicine · 2015 · 127 citations · Full text

Redox Signaling, Signal Transduction, Molecular Physiology +13

Interleukin-6 trans-signaling inhibition prevents oxidative stress in a mouse model of early diabetic retinopathy

Rebekah Robinson, Mukund P. Srinivasan, Arul Shanmugam et al. · Redox Biology · 2020 · 90 citations · Full text

Sigma receptor 1 modulates ER stress and Bcl2 in murine retina

Yonju Ha, Arul Shanmugam, Shanu Markand et al. · Cell and Tissue Research · 2014 · 50 citations · Full text

Photoreceptor Cell, Signal Transduction, Molecular Physiology +10

Sigma receptor 1 activation attenuates release of inflammatory cytokines <scp>MIP</scp>1γ, <scp>MIP</scp>2, <scp>MIP</scp>3α, and <scp>IL</scp>12 (p40/p70) by retinal Müller glial cells

Arul Shanmugam, Jing Wang, Shanu Markand et al. · Journal of Neurochemistry · 2014 · 24 citations · Full text

Immunology, Immune Regulation, Immunologic Mechanism +21

Progesterone Receptor Membrane Component 1 (PGRMC1) Expression in Murine Retina

Arul Shanmugam, Barbara A. Mysona, Jing Wang et al. · Current Eye Research · 2015 · 11 citations · Full text