Cost models for future software life cycle processes: COCOMO 2.0

Barry Boehm, Bradford Clark, Ellis Horowitz, +3

Annals of Software Engineering

Software MaintenanceEngineeringSoftware EngineeringLife Cycle CostingSoftware Analysis +15

Hepatitis B virus genotypes and virologic response in 694 patients in phase III studies of adefovir dipivoxil1 1Gilead Sciences gratefully acknowledges the patients, investigators, and study site personnel who participated in clinical trials GS-98-437 and GS-98-438.

C. Westland, William E. Delaney, Huiling Yang, +9

Gastroenterology

Site PersonnelHepatologyViral HepatitisHepatitis BHepatitis +6

Renal safety of adefovir dipivoxil in patients with chronic hepatitis B: Two double-blind, randomized, placebo-controlled studies

Hassane Izzedine, Jean‐Sébastien Hulot, Vincent Launay‐Vacher, +7

Kidney International

Renal SafetyUrologyRenal FunctionMedicineViral Hepatitis +8

Amyloid precursor proteins protect neurons of transgenic mice against acute and chronic excitotoxic injuries in vivo

Eliezer Masliah, C. Westland, Edward Rockenstein, +5

Neuroscience

ImmunologyTransgenic MiceChronic Excitotoxic InjuriesBeta-amyloid Protein PrecursorHuman App +14

In vitro antiviral susceptibility of full-length clinical hepatitis B virus isolates cloned with a novel expression vector

Hong Yang, C. Westland, Shanshan Xiong, +1

Antiviral Research

Novel Expression VectorViral HepatitisImmunologyHepatitis BHepatitis +6

Activity of adefovir dipivoxil against all patterns of lamivudine‐resistant hepatitis B viruses in patients

C. Westland, Hao Yang, William E. Delaney, +8

Journal of Viral Hepatitis

ImmunologyHepatitis BPharmacotherapyHbv PolymeraseAntiviral Drug +19

Resistance surveillance of HBEAG— chronic hepatitis B (CHB) patients treated for two years with adefovir dipivoxil (ADV)

S. Xiong, Hongu Yang, C. Westland, +11

Journal of Hepatology

HepatologyViral HepatitisHepatitis BHepatitisResistance Surveillance +3

382 In vitro characterization and molecular modeling analysis of a novel adefovir resistance mutation RTN236T in the HBV polymerase

Hao Yang, Xiaole Qi, Kalyan Das, +7

Journal of Hepatology

Vitro CharacterizationViral ReplicationEngineeringMolecular VirologyViral Polymerase Structure +11

45 HBsAg seroconversion in adefovir dipivoxil (ADV) treated chronic hepatitis B (CHB) patients

M. Shiffman, Patrick Marcellin, L. Jeffers, +10

Journal of Hepatology

HepatologyViral HepatitisImmunologyHepatitis BHepatitis +6

Safety, antiviral activity and pharmacokinetics of JNJ-64530440, a novel capsid assembly modulator, as 4 week monotherapy in treatment-naive patients with chronic hepatitis B virus infection

Ed Gane, Christian Schwabe, Elina Berliba, +12

Journal of Antimicrobial Chemotherapy