Isadora M.M. de Melo

Potent naphthoquinones against antimony-sensitive and -resistant Leishmania parasites: Synthesis of novel α- and nor-α-lapachone-based 1,2,3-triazoles by copper-catalyzed azide–alkyne cycloaddition

Tiago T. Guimarães, Maria do Carmo F. R. Pinto, Juliane S. Lanza et al. · European Journal of Medicinal Chemistry · 2013 · 102 citations

Potent Naphthoquinones, Medicinal Chemistry, Nor-α-lapachone-based 1,2,3-Triazoles +9

1,2,3-Triazole-, arylamino- and thio-substituted 1,4-naphthoquinones: Potent antitumor activity, electrochemical aspects, and bioisosteric replacement of C-ring-modified lapachones

Eduardo H. G. da Cruz, Caio M.B. Hussene, Gleiston G. Dias et al. · Bioorganic & Medicinal Chemistry · 2014 · 75 citations

On the search for potential anti-Trypanosoma cruzi drugs: Synthesis and biological evaluation of 2-hydroxy-3-methylamino and 1,2,3-triazolic naphthoquinoidal compounds obtained by click chemistry reactions

Eufrânio N. da Silva Júnior, Isadora M.M. de Melo, Emilay B. T. Diogo et al. · European Journal of Medicinal Chemistry · 2012 · 71 citations · Full text

Medicinal Chemistry, Bioorganic Chemistry, Antiparasitic Agent +11

Potent antileukemic action of naphthoquinoidal compounds: evidence for an intrinsic death mechanism based on oxidative stress and inhibition of DNA repair

Bruno Coêlho Cavalcanti, Igor O. Cabral, Felipe Augusto Rocha Rodrigues et al. · Journal of the Brazilian Chemical Society · 2013 · 24 citations · Full text

Dna Damage, Apoptosis, Cell Death +16