Gregory A. Applegate

Mix-and-inject XFEL crystallography reveals gated conformational dynamics during enzyme catalysis

Medhanjali Dasgupta, Dominik Budday, Saulo H. P. de Oliveira et al. · Proceedings of the National Academy of Sciences · 2019 · 92 citations · Full text

Cysteine Thiolate, Biochemistry, Protein Assembly +14

Exploiting Enzymatic Dynamic Reductive Kinetic Resolution (DYRKR) in Stereocontrolled Synthesis

Gregory A. Applegate, David B. Berkowitz · Advanced Synthesis & Catalysis · 2015 · 91 citations

A new dehydrogenase from Clostridium acetobutylicum for asymmetric synthesis: dynamic reductive kinetic resolution entry into the Taxotère side chain

Gregory A. Applegate, Ross W. Cheloha, David Lee Nelson et al. · Chemical Communications · 2010 · 49 citations

Taxotère Side Chain, Biosynthesis, Bioorganic Chemistry +14

Combining a <i>Clostridial</i> Enzyme Exhibiting Unusual Active Site Plasticity with a Remarkably Facile Sigmatropic Rearrangement: Rapid, Stereocontrolled Entry into Densely Functionalized Fluorinated Phosphonates for Chemical Biology

Gregory A. Applegate, Guillaume Malik, David B. Berkowitz · Journal of the American Chemical Society · 2015 · 37 citations · Full text

A thiocyanopalladation/carbocyclization transformation identified through enzymatic screening: stereocontrolled tandem C–SCN and C–C bond formation

Guillaume Malik, Robert A. Swyka, Virendra Kumar Tiwari et al. · Chemical Science · 2017 · 25 citations · Full text