Phosphatidylinositol-3-OH Kinase (PI3K)/AKT2, activated in breast cancer, regulates and is induced by estrogen receptor alpha (ERalpha) via interaction between ERalpha and PI3K.

Mei Sun, June E. Paciga, R I Feldman, +6

PubMed

Breast OncologyPi3k InhibitorPhosphatidylinositol-3-oh KinaseTumor BiologySignaling Pathway +15

Vascular endothelial growth factor, platelet-derived growth factor, and insulin-like growth factor-1 promote rat aortic angiogenesis in vitro.

Roberto F. Nicosia, S V Nicosia, Melissa C. Smith

PubMed

Deacetylation of cortactin by SIRT1 promotes cell migration

Y Zhang, M Zhang, Huiqin Dong, +9

Oncogene

Cell RegulationCell MigrationTumor SuppressorMedicineCell Biology +2

AKT2, a member of the protein kinase B family, is activated by growth factors, v-Ha-ras, and v-src through phosphatidylinositol 3-kinase in human ovarian epithelial cancer cells.

A X Liu, Joseph R. Testa, Thomas C. Hamilton, +3

PubMed

Epidermal Growth FactorCancer BiologyTumor BiologyOvarian CancerSignaling Pathway +15

Uterine junctional zone: correlation between histologic findings and MR imaging.

H. Keith Brown, Bernard Stoll, S V Nicosia, +4

Radiology

Imaging AnatomyGynecological SurgeryMedical ImagingAdenomyosisHistopathology +9

Frequency of mutations in mismatch repair genes in a population-based study of women with ovarian cancer

Pal T, Akbari Mr, Peng Sun, +11

British Journal of Cancer

Vascular endothelial growth factor levels in ovarian cyst fluid correlate with malignancy.

Darcie A. Hazelton, Roberto F. Nicosia, S V Nicosia

PubMed

AngiogenesisCyst FluidGrowth FactorMedicinePathology +8

Inhibition of androgen receptor activity by histone deacetylase 4 through receptor SUMOylation

Yonghua Yang, Anfernee Tse, Pei Li, +6

Oncogene

ChromatinAndrogen Receptor ActivitySignal TransductionBiochemistryEpigenetic Regulation +13

The insulin-like growth factor 1 receptor induces transformation and tumorigenicity of ovarian mesothelial cells and down-regulates their Fas-receptor expression.

Domenico Coppola, Brook A. Saunders, Ling Fu, +2

PubMed

PathologyCell ProliferationCell GrowthReceptor Induces TransformationInsulin Signaling +15

The anatomy of missed breast cancers

Douglas S. Reintgen, Claudia G. Berman, C.E. Cox, +6

Surgical Oncology

Surgical OncologyBreast OncologyMedicineBreast ImagingBreast Cancer +4