Pad Chivukula

Systemic delivery of factor IX messenger RNA for protein replacement therapy

Suvasini Ramaswamy, Nina Tonnu, Kiyoshi Tachikawa et al. · Proceedings of the National Academy of Sciences · 2017 · 306 citations · Full text

Pharmacy, Hematology, Molecular Medicine +15

A single dose of self-transcribing and replicating RNA-based SARS-CoV-2 vaccine produces protective adaptive immunity in mice

Ruklanthi de Alwis, Esther S. Gan, Shiwei Chen et al. · Molecular Therapy · 2021 · 181 citations · Full text

Veterinary Medicine, Immunology, Infectious Diseases +17

Engineered tRNAs suppress nonsense mutations in cells and in vivo

Suki Albers, Elizabeth Cheresh Allen, Nikhil Bharti et al. · Nature · 2023 · 132 citations · Full text

Life Sciences, Biotechnology, Molecular Biology +17

Safety, immunogenicity and efficacy of the self-amplifying mRNA ARCT-154 COVID-19 vaccine: pooled phase 1, 2, 3a and 3b randomized, controlled trials

Nhân Thị Hồ, Steven G. Hughes, Van Thanh Ta et al. · Nature Communications · 2024 · 78 citations · Full text

Veterinary Medicine, Immunology, Infectious Diseases +17

A phase I/II randomized, double-blinded, placebo-controlled trial of a self-amplifying Covid-19 mRNA vaccine

Jenny G. Low, Ruklanthi de Alwis, Shiwei Chen et al. · npj Vaccines · 2022 · 61 citations · Full text

Veterinary Medicine, Immunology, Infectious Diseases +17