Tim Cloughesy

Assessing the significance of chromosomal aberrations in cancer: Methodology and application to glioma

Rameen Beroukhim, Gad Getz, Leia Nghiemphu et al. · Proceedings of the National Academy of Sciences · 2007 · 1.1K citations · Full text

Life Sciences, Genetics, Oncology +17

Antitumor Activity of Rapamycin in a Phase I Trial for Patients with Recurrent PTEN-Deficient Glioblastoma

Tim Cloughesy, Koji Yoshimoto, Phioanh L. Nghiemphu et al. · PLoS Medicine · 2008 · 591 citations · Full text

Medicine, Oncology, Pharmacology +14

Epidermal Growth Factor Receptor Activation in Glioblastoma through Novel Missense Mutations in the Extracellular Domain

Jeffrey C. Lee, Igor Vivanco, Rameen Beroukhim et al. · PLoS Medicine · 2006 · 369 citations · Full text

Medicine, Cancer Biology, Oncology +17

Phase II Pilot Study of Bevacizumab in Combination with Temozolomide and Regional Radiation Therapy for Up-Front Treatment of Patients With Newly Diagnosed Glioblastoma Multiforme: Interim Analysis of Safety and Tolerability

Albert Lai, Emese Filka, B. McGibbon et al. · International Journal of Radiation Oncology*Biology*Physics · 2008 · 184 citations

Medicine, Oncology, Radiation Oncology +17

De-Repression of <i>PDGFRβ</i> Transcription Promotes Acquired Resistance to EGFR Tyrosine Kinase Inhibitors in Glioblastoma Patients

David Akhavan, Alexandra L. Pourzia, Alex Nourian et al. · Cancer Discovery · 2013 · 142 citations · Full text

Medicine, Oncology, Pharmacology +17