Mahmoud E. S. Soliman

Thompson loop: opportunities for antitubercular drug design by targeting the weak spot in demethylmenaquinone methyltransferase protein

Adeniyi T. Adewumi, Opeyemi Soremekun, Mary B. Ajadi et al. · RSC Advances · 2020 · 30 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Delving into Zika virus structural dynamics – a closer look at NS3 helicase loop flexibility and its role in drug discovery

Pritika Ramharack, Sofiat Oguntade, Mahmoud E. S. Soliman · RSC Advances · 2017 · 29 citations · Full text

Life Sciences, Biology, Infectious Diseases +16

The irony of chirality – unveiling the distinct mechanistic binding and activities of 1-(3-(4-amino-5-(7-methoxy-5-methylbenzo[<i>b</i>]thiophen-2-yl)-7<i>H</i>-pyrrolo[2,3-<i>d</i>]pyrimidin-7-yl)pyrrolidin-1-yl)prop-2-en-1-one enantiomers as irreversible covalent FGFR4 inhibitors

Farideh Badichi Akher, Abdolkarim Farrokhzadeh, Fisayo A. Olotu et al. · Organic & Biomolecular Chemistry · 2019 · 26 citations

Pharmacy, Medicinal Chemistry, Pharmacology +16

Allosteric inhibition induces an open WPD-loop: a new avenue towards glioblastoma therapy

Clement Agoni, Pritika Ramharack, Mahmoud E. S. Soliman · RSC Advances · 2018 · 24 citations · Full text

Medicine, Oncology, Pharmacology +17

Does Size Really Matter? Probing the Efficacy of Structural Reduction in the Optimization of Bioderived Compounds – A Computational “Proof-of-Concept”

Fisayo A. Olotu, Geraldene Munsamy, Mahmoud E. S. Soliman · Computational and Structural Biotechnology Journal · 2018 · 19 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17