Edward M. Acton

Intensely potent morpholinyl anthracyclines

Edward M. Acton, George L. Tong, Carol W. Mosher et al. · Journal of Medicinal Chemistry · 1984 · 137 citations

Anticancer Specificity of Some Ellipticinium Salts against Human Brain Tumors in vitro

Edward M. Acton, V. L. Narayanan, Prabhakar Risbood et al. · Journal of Medicinal Chemistry · 1994 · 124 citations

Further studies on the generation of reactive oxygen species from activated anthracyclines and the relationship to cytotoxic action and cardiotoxic effects

J. William Lown, Hsiao-Hsiung Chen, James A. Plambeck et al. · Biochemical Pharmacology · 1982 · 114 citations

Medicine, Immunology, Pharmacology +10

Diminished superoxide anion generation by reduced 5-iminodaunorubicin relative to daunorubicin and the relationship to cardiotoxicity of the anthracycline antitumor agents

J. William Lown, Hsiao-Hsiung Chen, James A. Plambeck et al. · Biochemical Pharmacology · 1979 · 97 citations

Medicinal Chemistry, Biochemistry, Medicine +8

5-Iminodaunorubicin. Reduced cardiotoxic properties in an antitumor anthracycline

George L. Tong, David W. Henry, Edward M. Acton · Journal of Medicinal Chemistry · 1979 · 94 citations

Medicinal Chemistry, Biochemistry, Medicine +13