Giuseppe D. Tocchini-Valentini

Crystal structures of the vitamin D receptor complexed to superagonist 20-epi ligands

Giuseppe D. Tocchini-Valentini, Natacha Rochel, Jean‐Marie Wurtz et al. · Proceedings of the National Academy of Sciences · 2001 · 226 citations · Full text

Medicine, Biochemistry, Pharmacology +17

A large scale hearing loss screen reveals an extensive unexplored genetic landscape for auditory dysfunction

Michael R. Bowl, Michelle M. Simon, Neil J. Ingham et al. · Nature Communications · 2017 · 153 citations · Full text

Life Sciences, Genetics, Molecular Genetics +10

Crystal Structures of the Vitamin D Nuclear Receptor Liganded with the Vitamin D Side Chain Analogues Calcipotriol and Seocalcitol, Receptor Agonists of Clinical Importance. Insights into a Structural Basis for the Switching of Calcipotriol to a Receptor Antagonist by Further Side Chain Modification

Giuseppe D. Tocchini-Valentini, Natacha Rochel, Jean‐Marie Wurtz et al. · Journal of Medicinal Chemistry · 2004 · 112 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +16

Structure, function, and evolution of the tRNA endonucleases of Archaea: An example of subfunctionalization

Giuseppe D. Tocchini-Valentini, Paolo Fruscoloni, Glauco P. Tocchini‐Valentini · Proceedings of the National Academy of Sciences · 2005 · 95 citations · Full text

Life Sciences, Microbiology, Molecular Biology +17

Superagonistic Action of 14-epi-Analogs of 1,25-Dihydroxyvitamin D Explained by Vitamin D Receptor-Coactivator Interaction

Guy Eelen, Lieve Verlinden, Natacha Rochel et al. · Molecular Pharmacology · 2005 · 78 citations

Medicine, Medicinal Chemistry, Pharmacology +9