Ann Gustafsson

Redesign of substrate-selectivity determining modules of glutathione transferase A1–1 installs high catalytic efficiency with toxic alkenal products of lipid peroxidation

Lisa O. Nilsson, Ann Gustafsson, Bengt Mannervik · Proceedings of the National Academy of Sciences · 2000 · 79 citations

Life Sciences, Biochemistry, Molecular Biology +17

New crystal structures of human glutathione transferase A1-1 shed light on glutathione binding and the conformation of the C-terminal helix

E. Grahn, Marián Novotný, Emma Jakobsson et al. · Acta Crystallographica Section D Biological Crystallography · 2006 · 67 citations

Life Sciences, Biochemistry, Molecular Biology +12

The C-Terminal Region of Human Glutathione Transferase A1-1 Affects the Rate of Glutathione Binding and the Ionization of the Active-Site Tyr9

Ann Gustafsson, Maryam Etahadieh, Per Jemth et al. · Biochemistry · 1999 · 46 citations

Life Sciences, Biochemistry, Molecular Biology +15

Role of the Glutamyl α-Carboxylate of the Substrate Glutathione in the Catalytic Mechanism of Human Glutathione Transferase A1-1

Ann Gustafsson, Pär L. Pettersson, Leif Grehn et al. · Biochemistry · 2001 · 41 citations

Life Sciences, Biochemistry, Enzyme Mechanism +11

Benzoic acid derivatives induce recovery of catalytic activity in the partially inactive Met208Lys mutant of human glutathione transferase A1-1 1 1Edited by A. R. Fersht

Ann Gustafsson, Bengt Mannervik · Journal of Molecular Biology · 1999 · 35 citations

Life Sciences, Biochemistry, Molecular Biology +11