Hongxian Xie

The comparison of ZFNs, TALENs, and SpCas9 by GUIDE-seq in HPV-targeted gene therapy

Zifeng Cui, Hui Liu, Hongfeng Zhang et al. · Molecular Therapy — Nucleic Acids · 2021 · 51 citations · Full text

Life Sciences, Genetics, Molecular Biology +17

Risk stratification of cervical lesions using capture sequencing and machine learning method based on HPV and human integrated genomic profiles

Rui Tian, Zifeng Cui, Dan He et al. · Carcinogenesis · 2019 · 47 citations

Medicine, Genetics, Oncology +17

FrCas9 is a CRISPR/Cas9 system with high editing efficiency and fidelity

Zifeng Cui, Rui Tian, Zhaoyue Huang et al. · Nature Communications · 2022 · 42 citations · Full text

Life Sciences, Biotechnology, Genetics +17

Gene knock-out chain reaction enables high disruption efficiency of HPV18 E6/E7 genes in cervical cancer cells

Rui Tian, Jiashuo Liu, Weiwen Fan et al. · Molecular Therapy — Oncolytics · 2021 · 31 citations · Full text

Life Sciences, Biotechnology, Genetics +17

An effective vaginal gel to deliver CRISPR/Cas9 system encapsulated in poly (β-amino ester) nanoparticles for vaginal gene therapy

Gang Niu, Zhuang Jin, Chong Zhang et al. · EBioMedicine · 2020 · 30 citations · Full text

Life Sciences, Biotechnology, Genetics +17