Joseph P. Loftus

Oncogene-independent BCR-like signaling adaptation confers drug resistance in Ph-like ALL

Christian Hurtz, Gerald Wertheim, Joseph P. Loftus et al. · Journal of Clinical Investigation · 2020 · 58 citations · Full text

Medicine, Oncology, Pharmacology +14

Potent preclinical activity of FLT3-directed chimeric antigen receptor T-cell immunotherapy against <i>FLT3</i>- mutant acute myeloid leukemia and <i>KMT2A</i>-rearranged acute lymphoblastic leukemia

Lisa M Niswander, Zachary Graff, Christopher D. Chien et al. · Haematologica · 2022 · 51 citations · Full text

Life Sciences, Immunology, Oncology +17

Alternative splicing of its 5′-UTR limits CD20 mRNA translation and enables resistance to CD20-directed immunotherapies

Zhiwei Ang, Luca Paruzzo, Katharina E. Hayer et al. · Blood · 2023 · 44 citations · Full text

Life Sciences, Immunology, Molecular Biology +17

Combinatorial efficacy of entospletinib and chemotherapy in patient-derived xenograft models of infant acute lymphoblastic leukemia

Joseph P. Loftus, Anella Yahiaoui, Patrick A. Brown et al. · Haematologica · 2020 · 36 citations · Full text

Medicine, Oncology, Pharmacology +17

Orbital Debris: A Chronology

David S. F. Portree, Joseph P. Loftus · 1999 · 32 citations

Engineering, Aerospace Engineering, Astronomy +15