Jason Clark

A randomized, placebo‐controlled trial of infliximab plus methotrexate for the treatment of polyarticular‐course juvenile rheumatoid arthritis

Nicolino Ruperto, Daniel J. Lovell, Rubén Cuttica et al. · Arthritis & Rheumatism · 2007 · 411 citations

Medicine, Pediatrics, Pharmacotherapy +12

First-in-Human Phase I Study of the Oral Inhibitor of Indoleamine 2,3-Dioxygenase-1 Epacadostat (INCB024360) in Patients with Advanced Solid Malignancies

Gregory L. Beatty, Peter J. O’Dwyer, Jason Clark et al. · Clinical Cancer Research · 2017 · 318 citations · Full text

Medicine, Oncology, Pharmacology +14

Randomized, Double-Blind, Phase II Study of Ruxolitinib or Placebo in Combination With Capecitabine in Patients With Metastatic Pancreatic Cancer for Whom Therapy With Gemcitabine Has Failed

Herbert I. Hurwitz, Nikhil Uppal, Stephanie A. Wagner et al. · Journal of Clinical Oncology · 2015 · 287 citations · Full text

Medicine, Oncology, Pharmacology +16

A Phase I Pharmacokinetic and Pharmacodynamic Study of Dalotuzumab (MK-0646), an Anti-Insulin-like Growth Factor-1 Receptor Monoclonal Antibody, in Patients with Advanced Solid Tumors

Francesco Atzori, Josep Tabernero, Andrés Cervantes et al. · Clinical Cancer Research · 2011 · 121 citations · Full text

Medicine, Oncology, Pharmacology +17

Ruxolitinib + capecitabine in advanced/metastatic pancreatic cancer after disease progression/intolerance to first-line therapy: JANUS 1 and 2 randomized phase III studies

Herbert I. Hurwitz, Eric Van Cutsem, Johanna C. Bendell et al. · Investigational New Drugs · 2018 · 109 citations

Medicine, Oncology, Pharmacology +14