Kristoff Nieves

The Pregnane X Receptor and Indole-3-Propionic Acid Shape the Intestinal Mesenchyme to Restrain Inflammation and Fibrosis

Kyle L. Flannigan, Kristoff Nieves, Holly Szczepanski et al. · Cellular and Molecular Gastroenterology and Hepatology · 2022 · 87 citations · Full text

Life Sciences, Cell Biology, Pharmacology +12

The pregnane X receptor and its microbiota-derived ligand indole 3-propionic acid regulate endothelium-dependent vasodilation

Vivek Krishna Pulakazhi Venu, Mahmoud Saifeddine, Koichiro Mihara et al. · American Journal of Physiology-Endocrinology and Metabolism · 2019 · 76 citations · Full text

Medicine, Pharmacology, Cell Signaling +12

Colitis-associated microbiota drives changes in behaviour in male mice in the absence of inflammation

Fernando Vicentini, Jake C. Szamosi, Laura Rossi et al. · Brain Behavior and Immunity · 2022 · 38 citations

Life Sciences, Immunology, Microbiology +14

The xenobiotic sensing pregnane X receptor regulates tissue damage and inflammation triggered by <i>C difficile</i> toxins

Sarah L. Erickson, Laurie Alston, Kristoff Nieves et al. · The FASEB Journal · 2019 · 19 citations · Full text

Veterinary Medicine, Immunology, Infectious Diseases +17

Indole-3-propionic acid protects medium-diversity colitic mice via barrier enhancement preferentially over anti-inflammatory effects

Kristoff Nieves, Kyle L. Flannigan, Elizabeth M. Hughes et al. · American Journal of Physiology-Gastrointestinal and Liver Physiology · 2025 · 13 citations · Full text

Life Sciences, Immunology, Pharmacology +17