David S. Small

A comparison of prasugrel and clopidogrel loading doses on platelet function: magnitude of platelet inhibition is related to active metabolite formation

John T. Brandt, Christopher D. Payne, Stephen D. Wiviott et al. · American Heart Journal · 2006 · 570 citations

Medicine, Pharmacokinetics, Pharmacology +17

Effects of the Proton Pump Inhibitor Lansoprazole on the Pharmacokinetics and Pharmacodynamics of Prasugrel and Clopidogrel

David S. Small, Nagy A. Farid, Christopher D. Payne et al. · The Journal of Clinical Pharmacology · 2008 · 316 citations

Medicine, Pharmacokinetics, Pharmacology +10

Increased Active Metabolite Formation Explains the Greater Platelet Inhibition With Prasugrel Compared to High-dose Clopidogrel

Christopher D. Payne, Ying Grace Li, David S. Small et al. · Journal of Cardiovascular Pharmacology · 2007 · 167 citations

Medicine, Pharmacokinetics, Pharmacology +17

Safety, Pharmacokinetics, and Pharmacodynamics of Drotrecogin Alfa (Activated) in Children With Severe Sepsis

Phil Barton, André C. Kalil, Simon Nadel et al. · PEDIATRICS · 2004 · 125 citations

Pharmacy, Pharmacokinetics, Pharmacology +17

The use of the VerifyNow P2Y12 point-of-care device to monitor platelet function across a range of P2Y12 inhibition levels following prasugrel and clopidogrel administration

Christopher D. Payne, Ying G. Li, John T. Brandt et al. · Thrombosis and Haemostasis · 2008 · 120 citations

Medicine, Pharmacology, Pharmacotherapy +17