Yi Chu

Dysfunctional autophagy in RPE, a contributing factor in age-related macular degeneration

Nady Golestaneh, Yi Chu, Yang-Yu Xiao et al. · Cell Death and Disease · 2017 · 353 citations · Full text

Life Sciences, Cell Biology, Ophthalmology +17

Dysregulated metabolic pathways in age-related macular degeneration

Meng Zhang, Nisi Jiang, Yi Chu et al. · Scientific Reports · 2020 · 135 citations · Full text

Life Sciences, Biochemistry, Ophthalmology +17

Repressed SIRT1/PGC-1α pathway and mitochondrial disintegration in iPSC-derived RPE disease model of age-related macular degeneration

Nady Golestaneh, Yi Chu, Shuk Kei Cheng et al. · Journal of Translational Medicine · 2016 · 125 citations · Full text

Health Professions, Molecular Biology, Ophthalmology +17

<i>Pgc-1α</i> repression and high-fat diet induce age-related macular degeneration-like phenotypes in mice

Meng Zhang, Yi Chu, Joseph Mowery et al. · Disease Models & Mechanisms · 2018 · 61 citations · Full text

Medicine, Ophthalmology, Vision Science +17

N-acetylcysteine protects human periodontal ligament fibroblasts from pyroptosis and osteogenic differentiation dysfunction through the SIRT1/NF-κB/Caspase-1 signaling pathway

Yi Chu, Yao Xu, Wanrong Yang et al. · Archives of Oral Biology · 2023 · 15 citations

Dentistry, Oral Biology, Periodontology +13