C.E.M. Stevenson

New insights into the binding mode of pyridine-3-carboxamide inhibitors of E. coli DNA gyrase

Sarah Narramore, C.E.M. Stevenson, Anthony Maxwell et al. · Bioorganic & Medicinal Chemistry · 2019 · 107 citations

Life Sciences, Biochemistry, Medicinal Chemistry +13

Bacterial Rotary Export ATPases Are Allosterically Regulated by the Nucleotide Second Messenger Cyclic-di-GMP

Eleftheria Trampari, C.E.M. Stevenson, Richard Little et al. · Journal of Biological Chemistry · 2015 · 96 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +5

A Crystal Structure of the Bifunctional Antibiotic Simocyclinone D8, Bound to DNA Gyrase

Marcus J. Edwards, Ruth H. Flatman, Lesley A. Mitchenall et al. · Science · 2009 · 88 citations

Life Sciences, Biochemistry, Medicinal Chemistry +13

Identification and Structure of the Anti-sigma Factor-binding Domain of the Disulphide-stress Regulated Sigma Factor σR from Streptomyces coelicolor

Wěi Li, C.E.M. Stevenson, Nicolas P. Burton et al. · Journal of Molecular Biology · 2002 · 62 citations

Life Sciences, Biochemistry, Microbiology +8

Discovery and Hit-to-Lead Optimization of Benzothiazole Scaffold-Based DNA Gyrase Inhibitors with Potent Activity against <i>Acinetobacter baumannii</i> and <i>Pseudomonas aeruginosa</i>

Andrej Emanuel Cotman, Martina Durcik, Davide Benedetto Tiz et al. · Journal of Medicinal Chemistry · 2023 · 54 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +16