TN Johnson

Predictive Performance of Physiologically Based Pharmacokinetic and Population Pharmacokinetic Modeling of Renally Cleared Drugs in Children

Wangchi Zhou, TN Johnson, Hongmei Xu et al. · CPT Pharmacometrics & Systems Pharmacology · 2016 · 83 citations · Full text

Characterization of Contributing Factors to Variability in Morphine Clearance Through PBPK Modeling Implemented With OCT1 Transporter

Chie Emoto, Tsuyoshi Fukuda, TN Johnson et al. · CPT Pharmacometrics & Systems Pharmacology · 2016 · 56 citations · Full text

Development of a Pediatric Physiologically Based Pharmacokinetic Model for Sirolimus: Applying Principles of Growth and Maturation in Neonates and Infants

Chie Emoto, Tsuyoshi Fukuda, TN Johnson et al. · CPT Pharmacometrics & Systems Pharmacology · 2015 · 39 citations · Full text

Pediatric Physiologically, Physiologically-based Pharmacokinetic Modeling, Pharmacodynamic Modeling +16

From Pediatric Covariate Model to Semiphysiological Function for Maturation: Part II—Sensitivity to Physiological and Physicochemical Properties

EHJ Krekels, TN Johnson, Sandra den Hoedt et al. · CPT Pharmacometrics & Systems Pharmacology · 2012 · 37 citations · Full text

Scaling Drug Clearance from Adults to the Young Children for Drugs Undergoing Hepatic Metabolism: A Simulation Study to Search for the Simplest Scaling Method

Elisa A. M. Calvier, Elke H. J. Krekels, TN Johnson et al. · The AAPS Journal · 2019 · 23 citations · Full text